120161-06-0

Basic information

• Product Name: 1H-Benzimidazole,2-(1-pyrrolidinyl)-(9CI)
• Synonyms: 1H-Benzimidazole,2-(1-pyrrolidinyl)-(9CI);2-(1-pyrrolidinyl)-1H-benzimidazole(SALTDATA: FREE);2-(1-pyrrolidinyl)-1H-benzimidazole
• CAS NO: 120161-06-0
• Molecular Formula: C₁₁H₁₃N₃
• Molecular Weight: 187.245
• Product Categories: BENZIMIDAZOLE
• Mol File: 120161-06-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 371.9°C at 760 mmHg
• Flash Point: 178.7°C
• Appearance: /
• Density: 1.251g/cm³
• Vapor Pressure: 9.98E-06mmHg at 25°C
• Refractive Index: 1.684
• CAS DataBase Reference: 1H-Benzimidazole,2-(1-pyrrolidinyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole,2-(1-pyrrolidinyl)-(9CI)(120161-06-0)
• EPA Substance Registry System: 1H-Benzimidazole,2-(1-pyrrolidinyl)-(9CI)(120161-06-0)

Safety Data

• Hazardous Substances Data: 120161-06-0(Hazardous Substances Data)

Usage

Imidazole derivative

A compound derived from imidazole This classification means that 1H-Benzimidazole, 2-(1-pyrrolidinyl)-(9CI) is based on the imidazole structure, which is a five-membered ring containing two nitrogen atoms.

Benzene ring fusion

A benzene ring is attached to the imidazole ring This property indicates that the compound has a benzene ring (a six-membered ring with alternating single and double bonds) fused to the imidazole ring, which contributes to its structural complexity.

Imidazole nitrogen attachment

A pyrrolidine group is attached to the nitrogen atom in the imidazole ring This specific content suggests that the pyrrolidine group (a five-membered ring with one double bond and four single-bonded carbon atoms) is connected to the nitrogen atom in the imidazole ring, further contributing to the compound's structure.

Potential pharmaceutical applications

Possible use in drug development and pharmaceutical research Due to its structural features and potential biological activities, 1H-Benzimidazole, 2-(1-pyrrolidinyl)-(9CI) may have applications in the development of new drugs and pharmaceutical research.

Building block in organic synthesis

Can be used to create more complex chemical compounds This property indicates that 1H-Benzimidazole, 2-(1-pyrrolidinyl)-(9CI) can serve as a starting material for the synthesis of more complex organic compounds, which may have various applications in different fields.

Need for further research

Limited understanding of properties and potential uses This statement highlights that more research is required to fully understand the properties and potential applications of 1H-Benzimidazole, 2-(1-pyrrolidinyl)-(9CI).

InChI:InChI=1/C11H13N3/c1-2-6-10-9(5-1)12-11(13-10)14-7-3-4-8-14/h1-2,5-6H,3-4,7-8H2,(H,12,13)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 13932-58-6 1-pyrrolidinecarboximidamide 
• 615-42-9 1,2-Diiodobenzene 
• 1112311-84-8 2-(4-chlorobutylamino)benzimidazole 
• 123-75-1 pyrrolidine 
• 40828-54-4 1H-benzimidazole-2-sulfonic acid 
• 4857-06-1 2-chloro-1H-benzoimidazole 
• 409314-87-0 N,N-dimethylpyrrolidine-1-carboxamide 

Relevant articles and documents

Benzimidazole derivative and preparation method and application thereof

The invention discloses a benzimidazole derivative and a preparation method and the application thereof. The prepared benzimidazole derivative is capable of effectively reducing the relapse arte afterabstaining from morphine addiction, has a remarkable ef

Synthesis of 1(11)H-2,3,4,5-tetrahydro[1,3]diazepino[1,2-a]benzimidazole starting from benzimidazole-2-sulfonic acid. Intramolecular cyclization of 2-(δ-chlorobutylamino)benzimidazole

The intramolecular cyclization of 2-(δ-chlorobutylamino)benzimidazole (3c) follows the unusual pathway involving the predominant attack on the exocyclic amino group rather than on the much more nucleophilic endocyclic nitrogen atom. This reaction affords 2-pyrrolidinobenzimidazole and 1(11)H-2,3,4,5-tetrahydro[1,3]diazepino[1,2-a]benzimidazole as the major product and the by-product, respectively. The cyclization can be directed exclusively toward the annulation of the diazepine ring only after the acetylation of the amino group of compound 3c. According to the quantum chemical calculations, the unusual regioselectivity of the cyclization of chloramine 3c is associated primarily with a substantially less steric strain and the higher entropy of pyrrolidine transition states compared to diazepine transition states.

Amide substituted imidazoquinolines

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain amide functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.