1201675-03-7

Basic information

• Product Name: 6-Chloro-2-(4-tert-butoxycarbonylpiperazino) -4-(trifluoromethyl)pyridine
• Synonyms: 6-Chloro-2-(4-tert-butoxycarbonylpiperazino) -4-(trifluoromethyl)pyridine;6-Chloro-2-(4-tert-butoxycarbonylpiperazin-1-yl)-4-(trifluoromethyl)pyridine;tert-Butyl 4-[6-Chloro-4-(trifluoromethyl)-2-pyridyl]piperaz
• CAS NO: 1201675-03-7
• Molecular Formula: C15H19ClF3N3O2
• Molecular Weight: 365.7784696
• Mol File: 1201675-03-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 443.7±45.0 °C(Predicted)
• Appearance: /
• Density: 1.312±0.06 g/cm3(Predicted)
• PKA: 3.28±0.10(Predicted)
• CAS DataBase Reference: 6-Chloro-2-(4-tert-butoxycarbonylpiperazino) -4-(trifluoromethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloro-2-(4-tert-butoxycarbonylpiperazino) -4-(trifluoromethyl)pyridine(1201675-03-7)
• EPA Substance Registry System: 6-Chloro-2-(4-tert-butoxycarbonylpiperazino) -4-(trifluoromethyl)pyridine(1201675-03-7)

Safety Data

• Hazardous Substances Data: 1201675-03-7(Hazardous Substances Data)

Upstream product

• 39890-98-7 2,6-dichloro-4-(trifluoromethyl)pyridine 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Downstream Products

• 1201673-41-7 6-(4-tert-butoxycarbonylpiperazin-1-yl)-2'-cyclohexylamino-[2,4']bipyridinyl-4-trifluoromethane 

Relevant articles and documents

Methylpyrazole derivatives as RET inhibitor

The invention relates to a methylpyrazole derivative as an RET inhibitor, in particular to a compound as shown in a formula (I), a stereoisomer and pharmaceutically acceptable salt thereof, a preparation method and a pharmaceutical composition thereof. The compound of the formula (I) can be used for preventing or treating diseases mediated by abnormal RET activity.

2,4'-BIPYRIDINYL COMPOUNDS AS PROTEIN KINASE D INHIBITORS USEFUL FOR THE TREATMENT OF IA HEART FAILURE AND CANCER

The present invention provides novel organic compounds of Formula I: methods of use, and pharmaceutical compositions thereof.