1201762-07-3

Basic information

• Product Name: (S)-diethyl 1-phenyl-3-oxo-3-pyrrol-1-yl-propylphosphonate
• Synonyms: (S)-diethyl 1-phenyl-3-oxo-3-pyrrol-1-yl-propylphosphonate
• CAS NO: 1201762-07-3
• Molecular Weight: 335.34
• Mol File: 1201762-07-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-diethyl 1-phenyl-3-oxo-3-pyrrol-1-yl-propylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-diethyl 1-phenyl-3-oxo-3-pyrrol-1-yl-propylphosphonate(1201762-07-3)
• EPA Substance Registry System: (S)-diethyl 1-phenyl-3-oxo-3-pyrrol-1-yl-propylphosphonate(1201762-07-3)

Safety Data

• Hazardous Substances Data: 1201762-07-3(Hazardous Substances Data)

Upstream product

• 762-04-9 phosphonic acid diethyl ester 
• 949013-80-3 3-phenyl-1-pyrrol-1-yl-2-propen-1-one 

Downstream Products

• 1201762-33-5 (S)-diethyl 3-oxo-1-phenyl-3-(piperidin-1-yl)propylphosphonate 
• 1201762-36-8 (S)-3-(diethoxyphosphoryl)-3-phenylpropanoic acid 
• 1201762-31-3 (S)-methyl 3-(diethoxyphosphoryl)-3-phenylpropanoate 
• 1201762-34-6 C₂₀H₂₆NO₄P 

Relevant articles and documents

Azetidine-derived dinuclear zinc catalyzed asymmetric phospha-Michael addition of dialkyl phosphite to α,β-unsaturated carbonyl compounds

The asymmetric phospha-Michael addition of dialkyl phosphite to α,β-unsaturated carbonyl compounds by using an azetidine-derived dinuclear zinc catalyst was described. The catalyst was proved to be general and efficient for a broad spectrum of enones and α,β-unsaturated N-acylpyrroles. A series of phosphonate-containing compounds were generated with excellent enantioselectivities (up to 99% ee) and chemical yields (up to 99%) under mild conditions without using additives. The products were obtained with more than 95% ee for 23 examples of α,β-unsaturated carbonyl compounds. A positive nonlinear effect was observed and the possible mechanism was proposed.