120186-08-5

Upstream product

• 120186-02-9 C₂₄H₃₇NO₃Si 
• 120186-07-4 (7S,11R)-11-(tert-Butyl-dimethyl-silanyloxy)-2-((R)-2-hydroxy-1-phenyl-ethyl)-2-aza-spiro[5.5]undecan-7-ol 
• 115439-18-4 C₁₈H₂₃NO₃ 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 100-39-0 benzyl bromide 
• 120186-10-9 (7S,11R)-11-(tert-Butyl-dimethyl-silanyloxy)-2-aza-spiro[5.5]undecan-7-ol 

Downstream Products

• 49620-06-6 (+)-isonitramine 
• 120210-97-1 (R)-2-Benzyl-11-(tert-butyl-dimethyl-silanyloxy)-2-aza-spiro[5.5]undec-7-ene 
• 120186-09-6 Methanesulfonic acid (7S,11R)-2-benzyl-11-(tert-butyl-dimethyl-silanyloxy)-2-aza-spiro[5.5]undec-7-yl ester 

Relevant academic research and scientific papers

ASYMMETRIC SYNTHESIS XV: ENANTIOSPECIFIC SYNTHESIS OF (+) AND (-) ISONITRAMINES FROM A COMMON CHIRAL INTERMEDIATE.

The enantiospecific synthesis of (+) and (-) isonitramines 7 has been achieved from a common chiral intermediate 5; this key compound was formed by condensation of two molar equivalents of glutaraldehyde with one mole of (-) phenylglycinol.