1201935-36-5

Basic information

• Product Name: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine
• Synonyms: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine;1-(1-methyl-4-piperidinyl)-1H-Pyrazol-4-amine;1-(1-methylpiperidin-4-yl)pyrazol-4-amine
• CAS NO: 1201935-36-5
• Molecular Formula: C₉H₁₆N₄
• Molecular Weight: 180.25014
• EINECS: 200-258-5
• Mol File: 1201935-36-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 335.0±32.0 °C(Predicted)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.55±0.10(Predicted)
• CAS DataBase Reference: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine(1201935-36-5)
• EPA Substance Registry System: 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine(1201935-36-5)

Safety Data

• Hazardous Substances Data: 1201935-36-5(Hazardous Substances Data)

Usage

Description

1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine is a chemical compound with the molecular formula C10H16N4. It is a pyrazole derivative and contains a methylpiperidine group. 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine is significant in medicinal chemistry due to its selective inhibitory activity on certain enzymes, which positions it as a potential candidate for drug development. Its unique structure and properties make it a promising substance for further research and development within the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine is used as a research compound for its selective inhibitory activity on certain enzymes. This characteristic makes it valuable in the development of new drugs, particularly those targeting specific enzyme pathways related to various diseases.
Used in Drug Development:
In the field of drug development, 1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine serves as a potential lead compound. Its ability to selectively inhibit certain enzymes suggests that it could be instrumental in creating targeted therapies for conditions where these enzymes play a critical role in disease progression.
Used in Medicinal Chemistry Research:
1-(1-Methylpiperidin-4-yl)-1H-pyrazol-4-aMine is utilized as a subject of study in medicinal chemistry research. Scientists investigate its interactions with biological targets to understand its potential therapeutic applications and to design more effective drugs based on its chemical structure.

Upstream product

• 132710-79-3 1-methylpiperidin-4-yl-4-methylbenzenesulfonate 
• 106-52-5 N-methyl-4-hydroxypiperidine 
• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 1201916-87-1 4-(4-nitro-1H-pyrazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester 
• 1201935-35-4 1-methyl-4-(4-nitro-1H-pyrazol-1-yl)piperidine 

Downstream Products

• 1201933-99-4 2-((5-chloro-2-((1-(1-methyl-4-piperidyl)pyrazol-4-yl)amino)-4-pyridyl)amino)-N-methoxy-N-methyl-benzamide 
• 1453207-62-9 5-[2-(2,6-difluoro-3,5-dimethoxyphenyl)ethyl]-N-[1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl]pyrimidin-2-amine 
• 1566543-19-8 2-(2-(2-(5-chloro-2-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-ylamino)pyrimidin-4-yl)ethyl)phenyl)propanamide 

Relevant articles and documents

FGFR Inhibitor compounds and uses thereof

The invention relates to FGFR inhibitor compounds and uses thereof. , The application discloses a compound as shown in a formula (I). A compound, or an optical isomer, a geometric isomer, a tautomer or isomer mixture thereof, or a pharmaceutically acceptable salt thereof, or a prodrug thereof, or a metabolite thereof. The application further relates to the application of the compound in medicine.

Heterocyclic compound as well as preparation method and medical application thereof

The invention relates to a heterocyclic compound suitable for inhibiting or regulating Janus family kinase (JAK), in particular tyrosine kinase 2 (TYK2), a preparation method of the heterocyclic compound and application of the heterocyclic compound in medicine. Specifically, the present invention relates to a compound represented by a general formula (I), a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the compound or the pharmaceutically acceptable salt thereof, and a method of using the compound or the pharmaceutically acceptable salt thereof to treat and/or prevent Janus kinase-mediated related diseases, especially autoimmune diseases, inflammatory diseases and cancers and a method for preparing the compound or pharmaceutically acceptable salt thereof. The invention also relates to application of the compound or the pharmaceutically acceptable salt thereof or the pharmaceutical composition containing the compound or the pharmaceutically acceptablesalt thereof in preparation of drugs for treating and/or preventing Janus kinase mediated related diseases, especially autoimmune diseases, inflammatory diseases and cancers. Each substituent of thegeneral formula (I) is as defined in the specification.

HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF

Described herein are compounds that are inhibitors of autophagy and their use in the treatment of disorders such as cancers. (I)