1202-49-9Relevant articles and documents
Efficient one-pot synthesis of 2-substituted furans from 3,3-diethoxypropyne and aldehydes using a Ti(O-i-Pr)4/2i-PrMgCl reagent
Eom, Deok Ki,Choi, Seong Jib,An, Duk Keun
, p. 1141 - 1146 (2007)
A new, efficient and direct synthetic method for synthesizing 2-substituted furans using titanium-alkyne complex from easily preparable lithium propargyl alcohol derivatives derived from commercially available 3,3-diethoxypropyne, n-butyllithium and aldehydes by a Ti(O-i-Pr)4/2 i-PrMgCl reagent in 68-85percent yields.
The coupling of butylvinyltellurides with organometallic reagents catalysed by nickel complexes
Raminelli, Cristiano,Gargalaka Jr., Jo?o,Silveira, Cláudio C.,Comasseto, Jo?o V.
, p. 8801 - 8809 (2007)
Vinylic tellurides couple efficiently with sp, sp2 and sp3 hybridised organometallic compounds (Li, MgX and Zn species) in the presence of dichloro-bis(triphenylphosphine)nickel(II) as catalyst.
Synthesis method of monosubstituted or disubstituted furan derivatives
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Paragraph 0048-0050, (2021/09/29)
The invention relates to the field of medicine synthesis, and provides a synthesis method of monosubstituted or disubstituted furan derivatives, wherein the synthesis method can be used for synthesizing various furan derivatives with different substituent groups and has high flexibility. According to the synthesis method of the monosubstituted or disubstituted furan derivatives, 5-hydroxymethyl-[delta]2-isoxazoline derivative is used as a raw material in an acidic solvent, and the monosubstituted or disubstituted furan derivatives are synthesized in one step under the action of a metal reducing agent; and according to the method, the furan derivatives with different substituent groups can be synthesized by adopting the 5-hydroxymethyl-[delta]2-isoxazoline derivatives with different substituent groups, high flexibility is achieved, the technical scheme is simple in step and mild in reaction condition, synthesis of the furan derivatives can be achieved through a one-pot method, the reaction yield is high, and large-scale production is facilitated.
Aza-peterson olefinations: Rapid synthesis of (E)-alkenes
Britten, Thomas K.,Basson, Ashley J.,Roberts, Dean D.,McLaughlin, Mark G.
, p. 3535 - 3544 (2021/06/03)
An aza-Peterson olefination methodology to access 1,3-dienes and stilbene derivatives from the corresponding allyl- or benzyltrimethylsilane is described. Silanes can be deprotonated using Schlosser's base and added to N -phenyl imines or ketones to directly give the desired products in high yields.
