1202243-48-8Relevant academic research and scientific papers
Divergent Multistep Continuous Synthetic Transformations of Allylic Alcohol Enabled by Catalysts Immobilized in Ionic Liquid Phases.
Peris, Edgar,Porcar, Raúl,García-álvarez, Joaquín,Burguete, María Isabel,García-Verdugo, Eduardo,Luis, Santiago V.
, p. 1684 - 1691 (2019/04/03)
Two individual catalytic platforms (metal- and organo-catalyzed) based on the use of an ionic liquid phase were successfully integrated for the synthesis of α-cyano-amine and cyanohydrin trimethylsilyl ethers from allylic alcohol. The right combination of continuous flow processes enabled access to the divergent preparation of two alternative and interesting intermediate compounds from the same starting material.
Lewis base-catalyzed three-component Strecker reaction on water. An efficient manifold for the direct α-cyanoamination of ketones and aldehydes
Cruz-Acosta, Fabio,Santos-Exposito, Alicia,De Armas, Pedro,Garcia-Tellado, Fernando
experimental part, p. 6839 - 6841 (2010/03/25)
The first three-component organocatalyzed Strecker reaction operating on water has been developed. The manifold utilizes ketones (aldehydes) as the starting carbonyl component, aniline as the primary amine, acetyl cyanide as the cyanide source and N,N-dim
