1202868-30-1Relevant articles and documents
Gold catalyzed glycosidations for the synthesis of sugar acrylate/acrylamide hybrids and their utility
Thadke, Shivaji A.,Kar, Mritunjoy,Gupta, Sayam Sen,Hotha, Srinivas
body text, p. 1511 - 1518 (2011/08/08)
Propargyl glyco 1,2-orthoesters were exploited for the efficient synthesis of interesting glycomonomers such as glyco-acrylates and acrylamides using gold catalysts. It was observed that propargyl glyco 1,2-orthoesters with hydroxyethyl acrylates gives very good yield of the corresponding glyco-acrylates in a single step in the presence of catalytic amount of gold(III) catalyst; whereas, gold catalyzed glycosidation reaction on hydroxyethyl acrylamides was found to yield the corresponding acrylamidoyl 1,2-orthoester which was then converted to the corresponding glycol-acrylamide in the presence of catalytic amount of TMSOTf. Synthesized glyco-acrylate/ acrylamide monomers are shown to undergo thiolate addition as well as free radical polymerization.