120296-49-3

Basic information

• Product Name: N^α-(5-chloro-5,8-dideazapteroyl)-L-ornithine
• CAS NO: 120296-49-3
• Molecular Weight: 458.904
• Mol File: 120296-49-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N^α-(5-chloro-5,8-dideazapteroyl)-L-ornithine(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-(5-chloro-5,8-dideazapteroyl)-L-ornithine(120296-49-3)
• EPA Substance Registry System: N^α-(5-chloro-5,8-dideazapteroyl)-L-ornithine(120296-49-3)

Safety Data

• Hazardous Substances Data: 120296-49-3(Hazardous Substances Data)

Upstream product

• 57343-54-1 6-<(p-carboxyanilino)methyl>-5-chloro-2,4-diaminoquinazoline 
• 120296-62-0 (S)-2-{4-[(2-Amino-5-chloro-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-(2,2,2-trifluoro-acetyl)-amino]-benzoylamino}-5-tert-butoxycarbonylamino-pentanoic acid 
• 120296-60-8 5-Chloro-10-(trifluoroacetyl)-5,8-dideazapteroic acid 
• 120296-59-5 5-Chloro-5,8-dideazapteroic acid 
• 13650-49-2 N^δ-(tert-butoxycarbonyl)-L-ornithine 
• 120296-64-2 N^δ-(tert-Butyloxycarbonyl)-N^α-(5-chloro-5,8-dideazapteroyl)-L-ornithine 

Relevant articles and documents

Inhibition of Mammalian Folylpolyglutamate Synthetase and Human Dihydrofolate Reductase by 5,8-Dideaza Analogues of Folic Acid and Aminopterin Bearing a Terminal L-Ornithine

Six new 5,8-dideaza analogues of folic acid and aminopterin containing a terminal L-ornithine residue were prepared by using multistep synthetic sequences.Each was evaluated as an inhibitor of hog liver folylpolyglutamate synthetase and human dihydrofolat