1203-77-6Relevant academic research and scientific papers
Efficient solid-phase synthesis of disubstituted 1,3-dihydro-imidazol-2- ones
Rossé, Gérard,Strickler, Julie,Patek, Marcel
, p. 2167 - 2168 (2007/10/03)
A bromoacetal linker was used to achieve the synthesis of ureas on a solid support. The resulting ureido acetals were treated with TFA and were converted in an intramolecular cyclization via N-acyliminium ion to disubstituted 1,3-dihydro-imidazol-2-ones.
