120346-72-7

Basic information

• Product Name: S-phenyl α-bromothiopropionate
• Synonyms: S-phenyl α-bromothiopropionate
• CAS NO: 120346-72-7
• Molecular Weight: 245.14
• Mol File: 120346-72-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: S-phenyl α-bromothiopropionate(CAS DataBase Reference)
• NIST Chemistry Reference: S-phenyl α-bromothiopropionate(120346-72-7)
• EPA Substance Registry System: S-phenyl α-bromothiopropionate(120346-72-7)

Safety Data

• Hazardous Substances Data: 120346-72-7(Hazardous Substances Data)

Upstream product

• 108-98-5 thiophenol 
• 563-76-8 α-bromopropionyl bromide 
• 120346-57-8 (E)-1-phenylsulphonyl-1-phenylthioprop-1-ene 
• 15296-86-3 1-(phenylsulfanyl)methyl phenyl sulfone 
• 35453-12-4 phenyl phenylthiomethyl sulfoxide 
• 3561-67-9 bis(phenylthio)methane 
• 7148-74-5 2-Bromopropionyl chloride 
• 802294-64-0 propionic acid 
• 120346-61-4 (E)-3-methyl-2-phenylsulphonyl-2-phenylthiooxirane 

Downstream Products

• 120346-76-1 S-phenyl α-iodothiopropionate 
• 1256358-39-0 2-(triphenylphosphoranylidene)propanethioic acid S-phenyl ester 
• 92339-75-8 S-phenyl 2-hydroxy(thiopropanoate) 
• 52411-61-7 anti-S-phenyl 3-hydroxy-2-methyl-3-phenylpropanethioate 
• 52411-61-7 syn-S-phenyl 3-hydroxy-2-methyl-3-phenylpropanethioate 

Relevant articles and documents

Cu(II)-catalyzed acylation by thiol esters under neutral conditions: Tandem acylation-wittig reaction leading to a one-pot synthesis of butenolides

The first catalytic acylation of alcohols with a thiol ester present in Wittig reagents under neutral conditions catalyzed by the Cu(II) salt through a push-pull mechanism is reported. Furthermore, a new methodology for the one-pot lactonization of acyloins by a copper catalyst is developed. The synthetic utility of this method for the synthesis of natural products is shown.

Efficient radical oxygenation of α-lodocarboxylic acid derivatives

(equation presented) Treatment of α-iodocarboxylic acid derivatives with 2 equiv of triethylborane under oxygen atmosphere gives the corresponding α-hydroxy add derivatives This method is based on an iodine atom transfer from the ethyl radical, generated by the reaction of riethylborane and oxygen, with the α-iodocarbonyl compound. It offers several advantages over classical ionic substitution reactions: no elimanation product is observed tertiary iodides are efficiently converted to alcohos, and finally, this one-step procedure is working with substrates sensitive to nucleophiles.

Preparation of 2-Halogeno S-Phenyl Thioesters from 2-Phenylsulphonyl-2-phenylthiooxiranes. Crystal Structures of 2-Phenylsulphonyloxiranes

1-Phenylsulphonyl-1-phenylthioalkenes 8 are prepared with high stereoselectivity as (E) isomers in a one-pot process by reaction of phenyl phenylthiomethyl sulphone 9 with aldehydes, followed by elimination.Nucleophilic epoxidation of these alkenes with l