1203474-59-2Relevant academic research and scientific papers
Iron-catalyzed arylalkoxycarbonylation of N -aryl acrylamides with carbazates
Xu, Xiangsheng,Tang, Yucai,Li, Xiaoqing,Hong, Guo,Fang, Mingwu,Du, Xiaohua
, p. 446 - 451 (2014)
A novel arylalkoxycarbonylation of N-aryl acrylamides with carbazates leading to alkoxycarbonylated oxindoles has been developed. The reported reactions employ economical and environmentally benign FeCl2· 4H2O as a catalyst and easil
Synthesis of Diversely Functionalized Oxindoles Enabled by Migratory Insertion of Isocyanide to a Transient σ-Alkylpalladium(II) Complex
Kong, Wangqing,Wang, Qian,Zhu, Jieping
, p. 9714 - 9718 (2016/08/11)
Palladium-catalyzed intramolecular carbopalladation of N-aryl acrylamides followed by migratory insertion of an isocyanide-coordinated C(sp3)?Pd intermediate afforded an alkylimidoyl?PdIIcomplex, which can be intercepted by a nucleophile, including heteroarenes. In addition to amides, the alkylimidoyl?PdIIcomplex was successfully converted into esters, ketones, and bis-heterocyclic compounds. An unprecedented palladium-catalyzed enantioselective domino process involving isocyanide was also documented.
Synthesis of oxindole-3-acetates through iron-catalyzed oxidative arylalkoxycarbonylation of activated alkenes
Wang, Gao,Wang, Shan,Wang, Jian,Chen, Shan-Yong,Yu, Xiao-Qi
, p. 3466 - 3470 (2014/05/06)
An iron-catalyzed alkoxycarbonylation/cyclization reaction of N-arylacrylamides with carbazates has been developed. This new alkene difunctionalization reaction provides an efficient and straightforward method to obtain various ester-containing oxindoles.
