1203669-37-7

Basic information

• Product Name: 2-(4-methoxyphenyl)-1-phenylquinolin-4(1H)-one
• Synonyms: 2-(4-methoxyphenyl)-1-phenylquinolin-4(1H)-one
• CAS NO: 1203669-37-7
• Molecular Weight: 327.382
• Mol File: 1203669-37-7.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxyphenyl)-1-phenylquinolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxyphenyl)-1-phenylquinolin-4(1H)-one(1203669-37-7)
• EPA Substance Registry System: 2-(4-methoxyphenyl)-1-phenylquinolin-4(1H)-one(1203669-37-7)

Safety Data

• Hazardous Substances Data: 1203669-37-7(Hazardous Substances Data)

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 123-11-5 4-methoxy-benzaldehyde 
• 2910-87-4 1-(2-bromophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 62-53-3 aniline 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 5874-09-9 methyl (4-methoxyphenyl)carbodithioate 
• 1203669-21-9 1-(2-bromophenyl)-3-(4-methoxyphenyl)prop-2-yn-1-one 

Relevant articles and documents

Facile synthesis of antimalarial 1,2-disubstituted 4-quinolones from 1,3-bisaryl-monothio-1,3-diketones

A new strategy was developed to synthesize 1,2-disubstituted 4-quinolones in good yield starting from 1,3-bisaryl-monothio-1,3-diketone substrates. The synthesized compounds were evaluated for antimalarial activity using Plasmodium falciparum strains. All compounds, except for two, showed good activity. Of these, seven compounds exhibited an excellent antimalarial activity (IC50, 50, >50 μM). This journal is

Transition-metal-free solid phase synthesis of 1,2-disubstituted 4-quinolones via the regiospecific synthesis of enaminones

Herein, the transition-metal-free economical solid phase synthesis of 1,2-disubstituted 4-quinolones has been developed via the novel regiospecific synthesis of enaminones. Notably, a wide range of enaminones were synthesized via a silica-supported solid-

Buchwald-Hartwig coupling/Michael addition reactions: One-pot synthesis of 1,2-disubstituted 4-quinolones from chalcones and primary amines

The Buchwald-Hartwig coupling/Michael addition sequence has been successfully applied to the synthesis of functionalized 1,2-disubstituted 4-quinolones using Pd(OAc)2 as a catalyst and PPh3 as a ligand. Under these conditions, the intermediate products first formed from chalcones and primary amines underwent catalytic dehydrogenation to yield the 1,2-disubstituted 4-quinolones. Copyright

Palladium-catalyzed tandem amination reaction for the synthesis of 4-quinolones

(Figure presented) An efficient palladium-catalyzed tandem amlnatlon approach was developed In one step to afford functlonallzed 4-qulnolones In good to excellent ylelds from easlly accessible o-haloaryl acetylenlc ketones and primary amines.