120417-90-5Relevant academic research and scientific papers
Towards stable di-carba analogues of guanofosfocins
Duchek, Jan,Huang, Mu-Hua,Vasella, Andrea
, p. 2940 - 2942 (2011)
Guanofosfocins are strong inhibitors of chitin synthases, but also very prone to hydrolytic cleavage. Two advanced intermediates 15 and 20 for the synthesis of stable di-carba-guanofosfocins were prepared via ester 11. Acylation of the allylic C-glycoside
New Chirons from D-Glucose. Regio- and Diastereoselective C-C Bond Forming Reactions Exploiting Novel Aldotetrafuranose Acetates as Chiral Synthetic Equivalents of Tartaric Aldehydes
Dhavale, Dilip D.,Tagliavini, Emilio,Trombini, Claudio,Umani-Ronchi, Achille
, p. 4100 - 4105 (2007/10/02)
Two differentially protected tetrafuranose acetates 5 and 6 have been prepared from diacetone D-glucose in parallel short routes.They clearly act as chiral synthetic equivalents of D- and meso-tartaric aldehydes when exploited in Lewis acid promoted react
NOVEL SYNTHETIC EQUIVALENTS OF DIFFERENTIALLY PROTECTED TARTARIC ALDEHYDES. A SIMPLE ROUTE TO USEFUL C-4 CHIRAL SYNTHONS.
Dhavale, Dilip D.,Tagliavini, Emilio,Trombini, Claudio,Umani-Ronchi, Achille
, p. 6163 - 6166 (2007/10/02)
The synthesis of 4-acetoxy-3-O-benzyl-1,2-O-isopropylidene aldotetroses from D-glucose is reported.These synthetic equivalents of tartaric aldehydes are chemoselectively reduced at the acetoxylated center leading to a series of useful differentially protected C-4 chiral synthons.
