1204211-98-2Relevant academic research and scientific papers
Facile synthesis of 2-phenylquinoline-4-carboxamide derivatives with variant structural features
Islam, Rafiqul,Hossain, Md. Imran,Okamoto, Yoshinari,Nagamatsu, Tomohisa,Anraku, Kensaku,Okawara, Tadashi
, p. 693 - 708 (2014/04/03)
The quinoline scaffold is an important class of heterocyclic compounds that possesses diverse chemotherapeutic activities. Thus, the 2-phenylquinoline-4- carboxamide derivatives containing a variety of moieties, such as 2-(2-furanyl)-1,3,4-oxadiazole, N-(2-methylphenyl)-4-(3-pyridinyl)-2- pyrimidinamine, 4,4′-bithiazole, purine, adamantine and resorcinol, have been designed and synthesized via Suzuki coupling, acid-base coupling and other typical reactions.
STAT3 INHIBITOR CONTAINING QUINOLINECARBOXAMIDE DERIVATIVE AS ACTIVE INGREDIENT
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Page/Page column 50, (2011/06/24)
The present invention provides a STAT3 inhibitor containing as an active ingredient, a quinolinecarboxamide derivative represented by the formula (I) (in the formula, W represents a bond or an alkylene chain; X represents O, S, or NR34; and Rs
