1204331-40-7

Upstream product

• 1204331-39-4 4-[1-(furan-2-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoic acid 
• 107317-58-8 4-bromo-3-trifluoromethylbenzoic acid methyl ester 
• 161622-14-6 4-bromo-3-(trifluoromethyl)benzoic acid 
• 1204331-34-9 4-(4-cyano-2-trifluoromethyl-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 1204331-26-9 4-(4-methoxycarbonyl-2-trifluoromethylphenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 1204331-48-5 4-(4-methoxycarbonyl-2-trifluoromethylphenyl)piperidine-1-carboxylic acid tert-butyl ester 
• 1204331-38-3 4-[1-(furan-2-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoic acid methyl ester 
• 1204331-35-0 4-(4-carboxy-2-trifluoromethyl-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 1204331-27-0 4-(4-carboxy-2-trifluoromethylphenyl)piperidine-1-carboxylic acid tert-butyl ester 
• 1393368-52-9 4-piperidin-4-yl-3-trifluoromethyl-benzoic acid methyl ester hydrochloride 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 138647-49-1 4-Trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 1735-53-1 4-bromo-3-(trifluoromethyl)benzonitrile 
• 375853-82-0 tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate 

Relevant academic research and scientific papers

PYRROLIDINYL AND PIPERIDINYL COMPOUNDS USEFUL AS NHE-1 INHIBITORS

Disclosed are compounds of formula (I) and compositions of the present invention which are inhibitors of the sodium proton exchanger isoform-1 (NHE-I). Also disclosed are methods of using and making the same.