1204401-08-0Relevant academic research and scientific papers
METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF
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Page/Page column 8-9, (2012/07/27)
Methods for synthesis and preparation of alpha-glycosphingolipids are provided. Methods for synthesis of α-galactosyl ceramide, and pharmaceutically active analogs and variants thereof are provided. Novel alpha-glycosphingolipids are provided, wherein the compounds are immunogenic compounds which serve as ligands for NKT (natural killer T) cells.
In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models
Lin, Kun-Hsien,Liang, Jian-Jong,Huang, Wen-I.,Lin-Chu, Shao-Ying,Su, Ching-Yao,Lee, Yi-Ling,Jan, Jia-Tsong,Lin, Yi-Ling,Cheng, Yih-Shyun E.,Wong, Chi-Huey
, p. 4129 - 4136 (2011/10/18)
Alpha-galactosyl ceramide (α-GalCer) has been known to bind to the CD1d receptor on dendritic cells and activate invariant natural killer T (iNKT) cells, which subsequently secrete T-helper-cell 1 (Th1) and Th2 cytokines, which correlate with anti-infecti
