1204527-69-4

Basic information

• Product Name: C₅₀H₇₁N₃O₉
• Synonyms: C₅₀H₇₁N₃O₉
• CAS NO: 1204527-69-4
• Molecular Weight: 858.128
• Mol File: 1204527-69-4.mol

Chemical Properties

• CAS DataBase Reference: C₅₀H₇₁N₃O₉(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₀H₇₁N₃O₉(1204527-69-4)
• EPA Substance Registry System: C₅₀H₇₁N₃O₉(1204527-69-4)

Safety Data

• Hazardous Substances Data: 1204527-69-4(Hazardous Substances Data)

Upstream product

• 117168-60-2 (2S)-2-azido-2-((4S)-2,2-dimethyl-5-tetradecyl-1,3-dioxolan-4-yl)ethan-1-ol 
• 143826-39-5 6-O-acetyl-2,3,4-tri-O-benzyl-α-D-galactopyranosyl trichloroacetimidate 
• 88567-49-1 6-O-acetyl-2,3,4-tri-O-benzyl-α/β-D-galactopyranoside 
• 28244-94-2 4-methylphenyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-galactopyranoside 
• 4163-60-4 β-D-galactose peracetate 
• 600168-67-0 2-azido-3,4-O-isopropylidene-1-O-triphenylmethyl-D-arabino-octadecane-1,3,4-triol 
• 86657-56-9 n-tridecylidenetriphenylphosphorane 
• 160280-62-6 3,4-O-isopropylidene-1-O-triphenylmethyl-D-arabino-octadec-5-en-1,2,3,4-tetraol 
• 13266-02-9 n-tridecyltriphenylphosphonium bromide 
• 765-09-3 1-bromotridecane 
• 1159181-00-6 p-tolyl 2,3,4-tri-O-benzyl-7-O-methyl-6-deoxy-1-thio-β-D-galacto-hept-6-enopyranoside 

Downstream Products

• 1204401-08-0 1-O-(α-D-galactopyranosyl)-2-(11-(4-(4-fluorophenoxy)phenyl)undecanoyl)amino-D-ribo-octadecane-1,3,4-triol 
• 1316751-64-0 C₇₃H₁₀₀FNO₁₁ 
• 1384423-78-2 1-O-(α-D-galactopyranosyl)-2-(11-(4-phenoxyphenyl)undecanoyl)amino-D-ribo-1,3,4-octadecanetriol 

Relevant articles and documents

Design, Synthesis, and Biological Evaluation of Ganglioside Hp-s1 Analogues Varying at Glucosyl Moiety

Ganglioside Hp-s1 is isolated from the ovary of sea urchin Diadema setosum. It exhibited better neuritogenic activity than GM1 in pheochromocytoma 12 cells. To explore the roles of glucosyl moiety of Hp-s1 in contributing to the neurogenic activity, we developed feasible procedures for synthesis of Hp-s1 analogues (2a-2f). The glucosyl moiety of Hp-s1 was replaced with α-glucose, α-galactose, β-galactose, α-mannose, and β-mannose, and their biological activities on SH-SY5Y cells and natural killer T (NKT) cells were evaluated. We found that the orientation of C-2 hydroxyl group at glucosyl moiety of Hp-s1 plays an important role to induce neurite outgrowth of SH-SY5Y cells. Surprisingly, compound 2d could activate NKT cells to produce interleukin 2, although it did not show great activity on neurite outgrowth of SH-SY5Y cells. In general, the Hp-s1 might be considered as a lead compound for the development of novel drugs aimed at modulating the activity of neuronal cells.

HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS

Glycosphingolipids (GSLs) compositions and methods for iNKT-independent induction of chemokines are disclosed.

In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models

Alpha-galactosyl ceramide (α-GalCer) has been known to bind to the CD1d receptor on dendritic cells and activate invariant natural killer T (iNKT) cells, which subsequently secrete T-helper-cell 1 (Th1) and Th2 cytokines, which correlate with anti-infecti