1204416-98-7

Basic information

• Product Name: C₃₂H₄₀N₄O₆S
• Synonyms: C₃₂H₄₀N₄O₆S
• CAS NO: 1204416-98-7
• Molecular Weight: 608.759
• Mol File: 1204416-98-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₂H₄₀N₄O₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₄₀N₄O₆S(1204416-98-7)
• EPA Substance Registry System: C₃₂H₄₀N₄O₆S(1204416-98-7)

Safety Data

• Hazardous Substances Data: 1204416-98-7(Hazardous Substances Data)

Upstream product

• 2620-27-1 1,5-bis(methylamino)-3-oxapentane 
• 1204417-91-3 tert-butyl 3-cyclohexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-6-carboxylate 
• 958002-18-1 1H-indole-6-carboxylic acid, 3-cyclohexyl-2-(2-formyl-4-methoxyphenyl)-, 1,1-dimethylethyl ester 
• 928844-30-8 13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid 10-(1,1-dimethylethyl) ester 6-methyl ester 
• 1204417-25-3 13-cyclohexyl-3-methoxy-6-[[methyl[2-[2-(methylamino)ethoxy]ethyl]amino]carbonyl]-7H-Iindolo[2,1-a][2]benzazepine-10-carboxylic acid, 1,1-dimethylethyl ester 
• 1038924-00-3 7H-indolo[2,1-a][2]benzazepine-6,10-dicarboxylic acid, 13-cyclohexyl-3-methoxy-, 10-(1,1-dimethylethyl) ester 
• 1204417-27-5 6-[[[2-[2-[(aminosulfonyl)methylamino]ethoxy]ethyl]methylamino]carbonyl]-13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid 
• 1204417-26-4 6-[[[2-[2-[(aminosulfonyl)methylamino]ethoxy] ethyl]methylamino]carbonyl]-13-cyclohexyl-3-methoxy-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid, 1,1-dimethylethyl ester 
• 1204417-28-6 C₃₅H₄₂N₆O₆S 
• 1204416-97-6 2,19-methano-3,7:4,1-dimetheno-1H,11H-14,10,2,9,11,17-benzoxathiatetraazacyclodocosine-8,18(9H,15H)-dione, 27-cyclohexyl-12,13,16,17-tetrahydro-22-methoxy-11,17-dimethyl-, 10,10-dioxide 

Downstream Products

• 1204416-99-8 (19R)-2,19-methano-3,7:4,1-dimetheno-1H,11H-14,10,2,9,11,17-benzoxathiatetraazacyclodocosine-8,18(9H,15H)-dione 27-cyclohexyl-12,13,16,17,19,20-hexahydro-22-methoxy-11,17-dimethyl-10,10-dioxide 
• 1204417-00-4 (19S)-2,19-methano-3,7:4,1-dimetheno-1H,11H-14,10,2,9,11,17-benzoxathiatetraazacyclodocosine-8,18-(9H,15H)-dione 27-cyclohexyl-12,13,16,17,19,20-hexahydro-22-methoxy-11,17-dimethyl-10,10-dioxide 

Relevant articles and documents

Finger loop inhibitors of the HCV NS5b polymerase. Part II. Optimization of tetracyclic indole-based macrocycle leading to the discovery of TMC647055

Optimization of a novel series of macrocyclic indole-based inhibitors of the HCV NS5b polymerase targeting the finger loop domain led to the discovery of lead compounds exhibiting improved potency in cellular assays and superior pharmacokinetic profile. F