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928844-30-8

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928844-30-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 928844-30-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,8,8,4 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 928844-30:
(8*9)+(7*2)+(6*8)+(5*8)+(4*4)+(3*4)+(2*3)+(1*0)=208
208 % 10 = 8
So 928844-30-8 is a valid CAS Registry Number.

928844-30-8Downstream Products

928844-30-8Relevant articles and documents

A practical and efficient synthesis of 6-carboalkoxy-13-cycloalkyl-5H- indolo[2,1-a][2]benzazepine-10-carboxylic acid derivatives

Hewawasam, Piyasena,Tu, Yong,Hudyma, Thomas W.,Zhang, Xiaofan,Gentles, Robert G.,Kadow, John F.,Meanwell, Nicholas A.

, p. 1148 - 1153 (2014/02/14)

A convenient and practical synthesis of 6-carboalkoxy-13-cycloalkyl-5H- indolo[2,1-a][2]benzazepine-10-carboxylic acid derivatives (6) has been developed. The key step in the synthesis utilizes an intramolecular tandem reaction sequence of a Michael addition followed by a Horner-Wadsworth-Emmons (HWE) olefination reaction between hemi-aminal 11 and methyl 2-(dimethoxyphosphoryl)acrylate 12. The ring construction occurred efficiently and purification of the products 6 was straightforward. The C-10 methyl ester of 6a was hydrolyzed selectively to the carboxylic acid 13 while the olefin of 6d was converted to the cyclopropane 14 using trimethylsulfoxonium iodide in DMSO in the presence of NaH.

Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors

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Page/Page column 55, (2010/09/05)

The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Compounds for the Treatment of Hepatitis C

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Page/Page column 32-33, (2009/05/28)

The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.

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