120448-41-1

Upstream product

• 111149-31-6 (3R,4S)-(E)-7-benzyloxy-4-methyl-1-trimethylsilylhept-5-en-1-yn-3-ol 
• 131101-47-8 (R)-5-Benzyloxy-4-hydroxy-2-pentyne 
• 120448-40-0 (R)-(Z)-1-benzyloxy-2-propargyloxy-3-pentene 
• 111149-29-2 (R)-(Z)-1-benzyloxy-2-(3'-trimethylsilylpropargyloxy)-3-pentene 
• 110339-29-2 (R)-(Z)-1-Benzyloxy-2-hydroxy-3-pentene 

Downstream Products

• 141207-20-7 Benzoic acid (E)-(1S,2S)-5-benzyloxy-1-ethynyl-2-methyl-pent-3-enyl ester 
• 111149-34-9 (4R,5S)-(2Z,6E)-8-benzyloxy-4-hydroxy-5-methyl-2,6-octadienoic acid lactone 
• 111149-35-0 (3S,4S,5S)-(E)-8-benzyloxy-4-hydroxy-3,5-dimethyloct-6-enoic acid lactone 
• 121896-41-1 methyl (4R,5S)-(2Z,6E)-8-benzyloxy-4-tert-butyldimethylsilyloxy-5-methylocta-2,6-dienoate 
• 121896-40-0 methyl (4R,5S)-(E)-8-benzyloxy-4-tert-butyldimethylsilyloxy-5-methyl-oct-6-en-2-ynoate 
• 121896-44-4 (E)-(3S,4S,5S)-8-Benzyloxy-3,5-dimethyl-oct-6-en-4-ol 
• 121896-50-2 (E)-(2S,3S,4R,5S)-8-Benzyloxy-3,5-dimethyl-oct-6-ene-2,4-diol 
• 121896-43-3 (4S,5S)-5-((E)-(S)-4-Benzyloxy-1-methyl-but-2-enyl)-4-methyl-tetrahydro-furan-2-ol 
• 121896-48-8 Methanesulfonic acid (3S,4R,5R)-5-((E)-(S)-4-benzyloxy-1-methyl-but-2-enyl)-4-methyl-2-oxo-tetrahydro-furan-3-yl ester 
• 121896-47-7 Benzoic acid (3S,4R,5R)-5-((E)-(S)-4-benzyloxy-1-methyl-but-2-enyl)-4-methyl-2-oxo-tetrahydro-furan-3-yl ester 
• 121960-66-5 (3S,4S,5R)-5-((E)-(S)-4-Benzyloxy-1-methyl-but-2-enyl)-3-hydroxy-4-methyl-dihydro-furan-2-one 
• 121896-46-6 (3R,4S,5R)-5-((E)-(S)-4-Benzyloxy-1-methyl-but-2-enyl)-3-hydroxy-4-methyl-dihydro-furan-2-one 
• 123372-88-3 (3R,4S)-7-Benzyloxy-4-methyl-heptan-3-ol 
• 141207-29-6 (2R,6R,8R,9S)-2-((2E,6E)-(R)-8-Benzyloxy-3,5-dimethyl-octa-2,6-dienyl)-8-ethyl-9-methyl-1,7-dioxa-spiro[5.5]undecan-4-one 

Relevant academic research and scientific papers

AN ENANTIOCONTROLLED ROUTE TO PROTOMYCINOLIDE IV AND ITS PRESUMED BIOGENETIC PRECURSORS USING (S)-O-BENZYLGLYCIDOL

Starting with (S)-O-benzylglycidol (9) as only chiral building block, a formal synthesis of protomycinolide IV (1) and the first syntheses of its presumed biogenetic precursors methyl epimycinonate I (2), methyl mycinonate I (3), methyl mycinonate II (4),

ENANTIOCONTROLLED SYNTHESIS OF THE C9-27 SEGMENT OF MILBEMYCIN K FROM (R)- AND (S)-EPICHLOROHYDRINS

The C9-27 segment (11) of milbemycin K (10) has been synthesized usintwo molar equivalents of (R)-epichlorohydrin -and one molar equivalent of (S)-epichlorohydrin (S)-1-as chiral building blocks.

A Route to Key Fragments of Mycoticin B and Amphotericin B from (S)-O-Benzylglycidol

A concise enantioselective synthesis of C27-34 fragment of mycoticin B and C31-37 fragment of amphotericin B is described using a common building block prepared from (S)-O-benzylglycidol.