120449-76-5

Basic information

• Product Name: N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide
• Synonyms: N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide
• CAS NO: 120449-76-5
• Molecular Weight: 478.143
• Mol File: 120449-76-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide(120449-76-5)
• EPA Substance Registry System: N'-benzylidene-2-(6,8-dibromo-2-methyl-4-oxoquinazolin-3(4H)-yl)acetohydrazide(120449-76-5)

Safety Data

• Hazardous Substances Data: 120449-76-5(Hazardous Substances Data)

Upstream product

• 40889-53-0 (6,8-dibromo-2-methyl-4-oxo-4H-quinazolin-3-yl)-acetic acid ethyl ester 
• 100-52-7 benzaldehyde 
• 40889-54-1 6,8-dibromo-2-methyl-4-oxo-3-quinazolineacetic acid hydrazide 

Downstream Products

• 120449-92-5 2-(6,8-Dibromo-2-methyl-4-oxo-4H-quinazolin-3-yl)-N-(4-oxo-2-phenyl-thiazolidin-3-yl)-acetamide 

Relevant articles and documents

Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity

This work presents the design and synthesis of a series of new quinazolin-4-one derivatives, based on the established effectiveness of quinazoline-based small molecules as anticancer agents. Synthesized compounds were more potent against MCF-7 than A-549