120449-76-5Relevant academic research and scientific papers
Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity
ElZahabi, Heba S.A.,Nafie, Mohamed S.,Osman, Dina,Elghazawy, Nehal H.,Soliman, Dalia H.,EL-Helby, Abdelghany Ali H.,Arafa, Reem K.
, (2021/06/15)
This work presents the design and synthesis of a series of new quinazolin-4-one derivatives, based on the established effectiveness of quinazoline-based small molecules as anticancer agents. Synthesized compounds were more potent against MCF-7 than A-549
Synthesis of 2-Methyl-4-oxo-N-(4-oxo-2-arylthiazolidin-3-yl)-3(4H)-quinazolineacetamides
Reddy, A. Malla,Achaiah, G.,Rao, A. Devendar,Reddy, V. Malla
, p. 1054 - 1056 (2007/10/02)
2-Methyl-4-oxo-N-(4-oxo-2-arylthiazolidin-3-yl)-3(4H)-quinazolineacetamides (3) have been synthesized by the reaction of 2-methyl-4-oxo-quinazoline-3-acetic acid arylidenehydrazides (2) with mercaptoacetic acid.The intermediate compounds (2) have been pre
