1204652-83-4

Upstream product

• 1198473-06-1 tert-butyl [5-chloro-2-[methoxy(methyl)carbamoyl]phenyl]carbamate 
• 136290-47-6 2-[(tert-butoxycarbonyl)amino]-4-chlorobenzoic acid 
• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 39061-72-8 2-acetyl-5-chloroaniline 
• 1204652-82-3 7-chloro-1-(2,4-difluorobenzyl)-3-[2-fluoro-3-(trifluoromethyl)phenyl]cinnolin-4(1H)-one 
• 1204652-87-8 3-bromo-7-chloro-1-(2,4-difluorobenzyl)cinnolin-4(1H)-one 
• 33844-20-1 3-bromo-8-methoxy-1H-cinnolin-4-one 
• 90417-27-9 8-methoxy-1H-cinnolin-4-one 

Relevant academic research and scientific papers

SUBSTITUTED 1-ALKYLCINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION OF SAME

The subject of the present invention is compounds corresponding to the formula (I) in which: X represents a divalent (C2-C5)alkylene radical which is unsubstituted or substituted one or more times by an Alk group; R1 represents a phenyl, a naphthyl, a pyridyl, a 1-benzothienyl or a 1,3-benzodioxolyl; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group or else a group chosen from —S-Alk, —SO-Alk, —SO2-Alk, —CO—N(R4)-Alk, —N(R4)SO2-Alk, —N(R4)CO-Alk, —N(R4)SO2—N(Alk)2; R3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 represents a hydrogen atom or a (C1-C4)alkyl; Alk represents an unsubstituted or substituted (C1-C4)alkyl. Preparation process and therapeutic application.

SUBSTITUTED 1-BENZYL-CINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF

The present invention is related to novel substituted 1-benzylcinnolin-4(1H)-one derivatives having affinity for cannabinoid CB2 receptors, their preparation and their therapeutic application.