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Usage

Uses

Used in Pharmaceutical Applications:
Resveratrol is utilized as a therapeutic agent for its potential role in the prevention and treatment of cardiovascular diseases, cancer, and neurodegenerative disorders. Its antioxidant and anti-inflammatory properties contribute to its efficacy in these areas, providing a natural alternative for supporting health and wellness.
Used in Cosmetic and Skincare Applications:
In the cosmetic and skincare industry, resveratrol is used as an active ingredient for its anti-aging and skin-protective qualities. It is valued for its ability to promote skin health and reduce the visible signs of aging, making it a popular choice for inclusion in anti-aging creams, serums, and other skincare formulations.
Used in Nutritional Supplements:
Resveratrol is also used as an ingredient in nutritional supplements, where it is marketed for its potential health benefits, including immune support, enhanced metabolism, and general well-being. Its antioxidant properties are particularly highlighted in this application, as they are believed to contribute to overall health and longevity.
Used in Research and Development:
Resveratrol is a subject of ongoing research and development, particularly in the fields of diabetes and obesity treatment. Its potential to modulate metabolic pathways and improve insulin sensitivity is being explored, with the aim of developing new therapeutic strategies for these prevalent health conditions.

Upstream product

• 75-16-1 methylmagnesium bromide 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 208937-71-7 [1-(2,5-Dimethoxy-phenyl)-vinyloxy]-diphenyl-silane 
• 1201-38-3 2',5'-dimethoxyacetophenone 

Downstream Products

• 14568-68-4 1,4-dimethoxy-2-vinylbenzene 
• 1201-38-3 2',5'-dimethoxyacetophenone 
• 64807-84-7 Methyl 2,2,5,5-Tetramethoxy-1,4-cyclohexadienecarboxylate 
• 72205-70-0 1-(2,2,5,5-Tetramethoxycyclohexadienyl)ethanol 
• 89691-52-1 C₂₀H₂₆O₄ 
• 89691-53-2 C₂₀H₂₆O₄ 
• 89691-34-9 C₁₆H₁₈O₄ 

Relevant academic research and scientific papers

Regiocontrol by Remote Substituents. A Direct Total Synthesis of Racemic Hongconin

The total synthesis of hongconin (1) has been completed.Key steps include the metalation of a benzylic alcohol, the formation of a six-membered ring ether via a mercury-mediated cyclization, and the regioselective installation of the naphthalene ring by way of a Diels-Alder reaction.

RETRACTED ARTICLE: The Manganese(I)-Catalyzed Asymmetric Transfer Hydrogenation of Ketones: Disclosing the Macrocylic Privilege

The bis(carbonyl) manganese(I) complex [Mn(CO)2(1)]Br (2) with a chiral (NH)2P2 macrocyclic ligand (1) catalyzes the asymmetric transfer hydrogenation of polar double bonds with 2-propanol as the hydrogen source. Ketones (43 substrates) are reduced to alcohols in high yields (up to >99 %) and with excellent enantioselectivities (90–99 % ee). A stereochemical model based on attractive CH–π interactions is proposed.

Rh(I)-catalysed asymmetric hydrosilylation using new oxazoline ligands with potential charge-transfer properties

Novel N′-methylated 2-(oxazolin-2-yl)-4,4′-bipyridinium salts, bearing a chiral oxazoline moiety, were tested in the Rh(I)-catalysed enantioselective hydrosilylation. After coordination to rhodium these electron-attracting ligands are supposed to exhibit charge-transfer effects with electron-donating substrates. Therefore, a new catalytic hydrosilylation reaction with 2,5-dimethoxyacetophenone as an electron-rich substrate was developed. The results were compared with those of the non-methylated 2-(oxazolin-2-yl)-4,4′-bipyridine and related ligands. In addition, the new ligands and Rh(I)-complexes were tested in the hydrosilylation of acetophenone.

A Reinvestigation of the Meerwein-Ponndorf-Verley Reduction: A Highly Efficient Variation Using Zirconium Catalysts

A new variation of the Meerwein-Ponndorf-Verley reduction based on mechanistic considerations is presented.Under optimized conditions 1-(4-dimethylaminophenyl)ethanol was used as the reducing alcohol (2-4 equiv.), Zr(O-tBu)4 as the catalyst (0.2 equiv.), and toluene or cyclohexane as the solvent.Aldehydes and ketones (if not extremely sterically hindered) were reduced to the corresponding alcohols at room temperature mostly within 2-4 h in essentially quantitative yield. α,β-Unsaturated carbonyl compounds cleanly react in a 1,2-mode to afford the corresponding allylic alcohols. - Key Words: Reductions / Meerwein-Ponndorf-Verley reaction / Catalysis / Zirconium tetra-tert-butoxide / β-Hydride shift / Kinetics

DEOXYGENATION OF ALDEHYDES AND KETONES WITH SODIUM CYANOBOROHYDRIDE

Treatment of hydroxy-substituted aromatic aldehydes and ketones with sodium cyanoborohydride yields the corresponding methylene compounds under conditions which favor intermediate carbonium ion formation.