120533-29-1 Usage
Description
THR 221C is a compound with various applications across different industries, particularly in the pharmaceutical and chemical sectors. It is known for its unique properties that make it suitable for a range of uses.
Uses
Used in Pharmaceutical Industry:
THR 221C is used as an impurity in the production of Cefodizime (C242865), a third-generation cephalosporin antibiotic. It possesses broad-spectrum antibacterial activity, making it effective against a wide range of bacterial infections.
THR 221C is used as an active ingredient for the treatment of various infections, such as:
1. Otitis media: THR 221C is used as an antibiotic to treat middle ear infections, providing relief from pain and inflammation.
2. Sinusitis: It is used as a therapeutic agent to alleviate symptoms of sinus infections, such as nasal congestion and facial pain.
3. Gynaecological infections: THR 221C is utilized as a treatment option for various gynecological infections, helping to eliminate harmful bacteria and promote overall reproductive health.
Used in Surgical Applications:
THR 221C is used as a prophylactic agent to prevent the occurrence of infections during and after surgical procedures. Its broad-spectrum antibacterial properties help to minimize the risk of postoperative complications and promote faster recovery.
Used in Chemical Industry:
In the chemical industry, THR 221C may be used as a raw material or intermediate in the synthesis of various compounds and products. Its specific applications may vary depending on the requirements of the industry and the desired end products.
Check Digit Verification of cas no
The CAS Registry Mumber 120533-29-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,5,3 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120533-29:
(8*1)+(7*2)+(6*0)+(5*5)+(4*3)+(3*3)+(2*2)+(1*9)=81
81 % 10 = 1
So 120533-29-1 is a valid CAS Registry Number.
120533-29-1Relevant articles and documents
NOVEL INTERMEDIATES FOR SYNTHESIS OF CEPHALOSPORINS AND PROCESS FOR PREPARATION OF SUCH INTERMEDIATES
-
Page 32, (2008/06/13)
A novel 4-halo-2-oxyimino-3-oxo butyric acid-N, N-dimethyl formiminium chloride chlorosulfate of formula (I) useful in the preparation of cephalosporin antibiotics, wherein X is chlorine or bromine; R is hydrogen, C1-4 alkyl group, an easily removable hydroxyl protective group, -CH2COOR5, or -C(CH3)2COOR5, wherein R5 is hydrogen or an easily hydrolysable ester group. The compound of formula (I) is prepared by reacting 4-halo-2-oxyimino-3-oxobutyric acid of formula (IV1), wherein X, R and R5 are as defined above, with N, N-dimethylformiminium chloride chlorosulphate of formula (VII), in an organic solvent at a temperature ranging from -30 °C to -15 °C. The cephalosporins that may be prepared from the intermediate include cefdinir, cefditoren pivoxil, cefepime, cefetamet pivoxil, cefixime, cefmenoxime, cefodizime, cefoselis, cefotaxime, cefpirome, cefpodoxime proxetil, cefquinome, ceftazidime, cefteram pivoxil, ceftiofur, ceftizoxime, ceftriaxone and cefuzonam.
Acidic degradation of cefodizime (THR-221) and structural elucidation of the products. I
Marunaka,Matsushima,Minami,Azuma,Yoshida,Umeno
, p. 367 - 372 (2007/10/02)
-
