120549-86-2Relevant academic research and scientific papers
Facile synthesis of oxamides by efficient trapping of carbamoyl lithiums with isocyanates
Mizuno,Matsumoto,Nishiguchi,Hirashima
, p. 2139 - 2144 (1993)
Unsymmetrical oxamides are conveniently synthesized in good yields by a new trapping reaction of unstable carbamoyl lithiums with isocyanates.
Photoinduced Cascade C-N/C═O Bond Formation from Bromodifluoroalkyl Reagents, Amines, and H2O via a Triple-Cleavage Process
Jin, Can,Li, Bingqian,Ling, Lan,Su, Weike,Sun, Bin,Wang, Yingying,Zhuang, Xiaohui
, p. 1668 - 1672 (2022/03/14)
A green, sustainable, and straightforward method for the synthesis of unsymmetrical oxalamides via photoinduced C-N/C═O bond formation of bromodifluoroacetamide, amine, and H2O through a triple-cleavage process has been developed. In addition, this approach also provides access to the known bioactive compounds, and a feasible reaction mechanism is proposed. Moreover, the advantages of this transformation, including mild reaction conditions, a broad substrate scope, and operational simplicity, make this protocol attractive for further applications.
