120563-92-0Relevant academic research and scientific papers
Optimization of methods for the generation of carbodiimides for zwitterionic 1,3-diaza-Claisen rearrangements
Walker, Joel D.,Madalengoitia, José S.
supporting information, p. 3786 - 3789 (2015/06/08)
Strained, tertiary, allylic, amine 2-benzyl-2-azabicyclo[2.2.1]hept-5-ene reacts with in situ generated carbodiimides in a 1,3-diaza-Claisen rearrangement to afford structurally interesting bicyclic guanidines. Use of more electron deficient carbodiimides makes these rearrangements more facile; however, there are not sufficient methods for the synthesis of highly electron deficient carbodiimides. Herein reported is the exploration of the synthesis of such carbodiimides from parent ureas and isothioureas and their use in 1,3-diaza-Claisen rearrangements.
Structure-Analytical Investigations of Consecutive Products of Sulfonamides. V. Infrared Spectroscopic and Thermoanalytical Studies of Polymorphic Modifications of N-Substituted S-Methyl-N'-tosyl-isothioureas
Reinke, H.,Hans, M.,Matos, E.,Dehne, H.
, p. 801 - 807 (2007/10/02)
Four compounds (1d, 1e, 1h, 1p) out of twelve N-substituted S-methyl-N'-tosyl-isothioureas were shown to form polymorphic modifications.Attempts were made to isolate each single specimen and to characterize it by means of differential scanning calorimetry and infrared spectroscopy.The results clearly revealed that both different hydrogen bonding and conformational effects are responsible for the formation of the polymorphic species.With the help of (15)N labeled compounds the presence of the sulfonylimino structure in any modification was proved.The ν(NH) and δS(SO2) band positions are used to divide the polymorphs into two groups A and B.
