2973-83-3Relevant academic research and scientific papers
Synthesis of Cyclic Guanidines Bearing N-Arylsulfonyl and N-Cyano Protecting Groups via Pd-Catalyzed Alkene Carboamination Reactions
Peterson, Luke J.,Luo, Jingyi,Wolfe, John P.
, p. 2817 - 2820 (2017)
Palladium-catalyzed carboamination reactions of N-allylguanidines bearing cleavable N-cyano or N-arylsulfonyl protecting groups are described. The reactions afford cyclic guanidine products in good yield, and transformations of substrates bearing internal alkenes proceed with high diastereoselectivity. Deuterium labeling studies indicate these transformations proceed via anti-aminopalladation pathways.
Intramolecular Formation of Zwitterionic Intermediates in 1,3-Diaza-Claisen Rearrangements
Walker, Joel D.,Watson, Rebecca,Flemer, Stevenson,Yang, Yanbo,Madalengoitia, José S.
supporting information, p. 4010 - 4013 (2017/08/14)
Isothioureas tethered to bridged-bicyclic tertiary allylic amines can be converted to carbodiimides through reaction with Hg(II) salts. Intramolecular cyclization of the tethered tertiary allylic amines to the carbodiimides afford zwitterionic intermediat
Synthesis of Cyclic Guanidines via Silver-Catalyzed Intramolecular Alkene Hydroamination Reactions of N-Allylguanidines
Garlets, Zachary J.,Silvi, Mattia,Wolfe, John P.
supporting information, p. 2331 - 2334 (2016/06/09)
The silver-catalyzed hydroamination of tosyl-protected N-allylguanidines is described. These reactions provide substituted cyclic guanidines in high yields. The reactions are amenable to the construction of quaternary stereocenters as well as both monocyc
Strukturanalytische Untersuchungen an Folgeprodukten aus Sulfonamiden VI - Kinetische Untersuchungen zur Reaktion von N-Arylsulfonyl-iminothiokohlensaeuremethylesterchloriden mit aliphatischen Aminen
Hans, M.,Imrich, J.,Barnikol, F.,Reinke, H.,Suchar, G.,et al.
, p. 1089 - 1097 (2007/10/02)
The reaction of a number of N-arylsulfonyl-iminothiocarbonic acid methylesterchloride compounds 1 with nucleophiles is studied by means of stopped-flow analysis.To clarify the reaction mechanism the influence of concentration, solvents and substituents on
