1205677-39-9

Upstream product

• 67-56-1 methanol 
• 595581-85-4 1-(4-methoxybenzyl)-3,5-dichloro-6-methyl-pyrazine-2(1H)-one 

Downstream Products

• 1262486-53-2 ((2R,3S,5R)-3-(4-chlorobenzoyloxy)-5-(4-(5-(3,4-dimethoxyphenyl)-6-methoxy-3-methylpyrazin-2-yl)-1H-1,2,3-triazol-1-yl)tetrahydrofuran-2-yl)methyl 4-chlorobenzoate 
• 1262486-52-1 (2R,3R,4R,5R)-2-(benzoyloxymethyl)-5-(4-(5-(3,4-dimethoxyphenyl)-6-methoxy-3-methylpyrazin-2-yl)-1H-1,2,3-triazol-1-yl)tetrahydrofuran-3,4-diyl dibenzoate 
• 1262486-51-0 (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-(4-(6-methoxy-5-(4-methoxyphenyl)-3-methylpyrazin-2-yl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 1262486-50-9 (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(4-(6-methoxy-5-(4-methoxyphenyl)-3-methylpyrazin-2-yl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 1262486-49-6 ((2R,3S,5R)-3-(4-chlorobenzoyloxy)-5-(4-(6-methoxy-5-(4-methoxyphenyl)-3-methylpyrazin-2-yl)-1H-1,2,3-triazol-1-yl)tetrahydrofuran-2-yl)methyl 4-chlorobenzoate 
• 1262486-46-3 2-ethynyl-6-methoxy-5-(3,4-dimethoxyphenyl)-3-methylpyrazine 
• 1262486-45-2 2-ethynyl-6-methoxy-5-(4-methoxyphenyl)-3-methylpyrazine 
• 1262486-40-7 2-(4-tert-butylphenyl)-5-chloro-3-methoxy-6-methylpyrazine 
• 1262486-39-4 2-chloro-6-methoxy-5-(3,4-dimethoxyphenyl)-3-methylpyrazine 
• 1262486-31-6 2-(4-methoxybenzylthio)-5-chloro-3-methoxy-6-methylpyrazine 
• 1262486-28-1 1-(4-methoxybenzyl)-5-chloro-3-methoxy-6-methylpyrazine-2(1H)-thione 
• 1205677-55-9 2-chloro-6-methoxy-5-(4-methoxyphenyl)-3-methylpyrazine 

Relevant academic research and scientific papers

Efficient preparation of tetrasubstituted pyrazines starting from pyrazin-2(1H)-ones

An efficient methodology for the synthesis of tetrasubstituted pyrazines starting from pyrazin-2(1H)-ones has been elaborated. Diversity in the functionalization and the beneficial effect of microwave irradiation throughout the methodology has been demonstrated. Georg Thieme Verlag Stuttgart · New York.

An expeditious route toward pyrazine-containing nucleoside analogues

An improved and convenient methodology for the synthesis of asymmetrically substituted pyrazines starting from 3,5-dichloropyrazin-2(1H)-ones has been elaborated. Several nucleoside analogues have been synthesized containing the pyrazine core as the organic base coupled with the sugar via a triazole linkage. The beneficial effect of microwave irradiation throughout the sequence has been demonstrated.

Microwave-assisted palladium-catalyzed phosphonium coupling of 2(1H)-pyrazinones

(Chemical Equation Presented) An expedient route for the synthesis of differently substituted 2(1H)-pyrazinones applying a microwave-assisted palladium-catalyzed phosphonium coupling procedure is reported.The method has also beensuccessfullyextended to some other tautomerizable heterocycles for efficient C-C cross-coupling.