1206-23-1

Upstream product

• 2761-33-3 2-acetoxytetrahydropyran 
• 7677-24-9 trimethylsilyl cyanide 
• 108-94-1 cyclohexanone 
• 110-87-2 3,4-dihydro-2H-pyran 
• 931-97-5 1-hydroxy-1-cyclohexanecarbonitrile 

Downstream Products

• 1126-99-4 1-(1-Hydroxy-cyclohexyl)-2-methyl-propan-1-on 
• 16113-13-6 3-benzyl-4-ethyl-1-oxa-3-aza-spiro[4.5]decan-2-one 
• 1145-99-9 1-<1-Hydroxy-2-methyl-1-phenyl-propyl>-cyclo-hexanol-(1) 
• 1142-69-4 1-<1-Hydroxy-1-phenyl-propyl>-cyclohexanol-(1) 
• 1130-15-0 (+/-)-2-<1-Hydroxy-cyclohexyl>-3-methyl-butan-2-ol 
• 1126-98-3 1-(α-Hydroxy-isobutyl)-cyclohexanol 
• 1197-71-3 (+/-)-1-Hydroxy-1-(1-hydroxy-1-methyl-propyl)-cyclohexan 
• 1124-89-6 1-(α-Oxy-propyl)-cyclohexanol-(1) 
• 16112-45-1 4'-Ethyl-cyclohexanoxazolidon-(2') 
• 689206-57-3 1-(1-amino-4-methyl-pentyl)-cyclohexanol 
• 1124-90-9 1-(1-hydroxycyclohexyl)propan-1-one 
• 16108-63-7 1-Valeryl-cyclohexanol-⁽¹⁾ 
• 802282-11-7 1-(1-amino-pentyl)-cyclohexanol 
• 102729-78-2 1-(α-Amino-benzyl)-cyclohexanol 

Relevant academic research and scientific papers

A mild and efficient tetrahydropyranylation of alcohols

Triphenylphosphine (TPP)-iodotrimethylsilane (TMSI) was found to be a convenient and highly effective catalyst for the tetrahydropyranylation of aliphatic and aromatic alcohols with dihydropyran in dichloromethane at ambient temperature.

Iron(III) triflate-catalyzed one-pot synthesis of acetal-type protected cyanohydrins from carbonyl compounds

A variety of cyanohydrin THP ethers were readily prepared from carbonyl compounds with trimethylsilyl cyanide and tetrahydropyran-2-yl acetate under the influence of a catalytic amount of iron(III) triflate in a convenient one-pot procedure. This method was also effective to prepare O-protected cyanohydrins by various acetal-type protective groups.