1124-90-9Relevant articles and documents
Efficient synthesis of tertiary α-hydroxy ketones through CO 2-promoted regioselective hydration of propargylic alcohols
He, Haitao,Qi, Chaorong,Hu, Xiaohan,Guan, Yuqi,Jiang, Huanfeng
supporting information, p. 3729 - 3733 (2014/08/05)
A carbon dioxide-promoted and silver acetate-catalyzed hydration of propargylic alcohols for the efficient synthesis of tertiary α-hydroxy ketones has been developed. The reaction is proposed to proceed via a tandem process of carbon dioxide incorporation into propargylic alcohols and subsequent hydrolysis. This journal is the Partner Organisations 2014.
Synthesis of α-Hydroxy Ketones by Samarium(II) Iodide-Mediated Coupling of Organic Halides, an Isocyanide, and Carbonyl Compounds
Murakami, Masahiro,Kawano, Teiji,Ito, Hajime,Ito, Yoshihiko
, p. 1458 - 1465 (2007/10/02)
A new strategy for the synthesis of α-hydroxy ketones by samarium(II) iodide-mediated three-component coupling of organic halides, an isocyanide, and carbonyl compounds is disclosed.An (α-iminoalkyl)samarium(III) species is generated in situ by treatment
SYNTHESIS OF 1,2-GLYCOL MONOETHERS UTILIZING DECARBONYLATION OF α-ALKOXYACID CHLORIDES MEDIATED BY SAMARIUM DIIODIDE
Sasaki, Mitsuru,Collin, Jacqueline,Kagan, Henri B.
, p. 4847 - 4850 (2007/10/02)
A new synthesis of 1,2-glycol monoethers has been achived by utilizing decarbonylation of α-alkoxyacid chlorides mediated by samarium diiodide in the presence of ketones.This one-pot reaction works within a few minutes at room temperature.The structure of α-alkoxyacid chlorides (R2,R3)C(OR1)COCl2 tolerates various substitution patterns (R2=R3=H; R2=H; R3=Me or R2=R3=Me).