120608-90-4

Basic information

• Product Name: 2-Fluoro-benzoic acid difluoromethyl ester
• Synonyms: 2-Fluoro-benzoic acid difluoromethyl ester
• CAS NO: 120608-90-4
• Molecular Weight: 190.122
• Mol File: 120608-90-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Fluoro-benzoic acid difluoromethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-benzoic acid difluoromethyl ester(120608-90-4)
• EPA Substance Registry System: 2-Fluoro-benzoic acid difluoromethyl ester(120608-90-4)

Safety Data

• Hazardous Substances Data: 120608-90-4(Hazardous Substances Data)

Upstream product

• 1717-59-5 2,2-difluoro-2-(fluorosulfonyl)acetic acid 
• 490-97-1 sodium 2-fluorobenzoate 

Relevant articles and documents

Perfluoro- and Polyfluorosulfonic Acids. 21. Synthesis of Difluoromethyl Esters Using Fluorosulfonyldifluoroacetic Acid as a Difluorocarbene Precursor

Difluoromethyl alkanoates 5 and fluorinated and nonfluorinated alkanesulfonates 9 were synthesized in moderate yields by the reaction of alkali metal salts of acids with fluorosulfonyldifluoroacetic acid (3) in acetonitrile under mild conditions.The presumed intermediate anion FO2SCF2CO2- generates CF2: by elimination of SO2, CO2, and F-.The esters are formed by insertion of CF2: into the O-H of the acid, whereas HCF3 is formed by the competing capture of F-.Organic acids can be used indirectly in the reaction in the presence of inorganic salts such as Na2SO4 and KCl, with comparable yields of difluoromethyl esters.