1206803-29-3Relevant academic research and scientific papers
Highly efficient and mild method for regioselective de-O-benzylation of saccharides by Co2(CO)8-Et3SiH-CO reagent system
Yin, Zhao-Jun,Wang, Bo,Li, Yang-Bing,Meng, Xiang-Bao,Li, Zhong-Jun
supporting information; experimental part, p. 536 - 539 (2010/05/02)
[Chemical equation presented] A highly efficient and mild method for the de-O-benzylation of protected saccharides was developed by transforming terminal benzyl ethers Into silyl ethers using Co2(CO)8-Et 3SIH under 1 atm of CO. The method was successfully used for the de-O-benzylatlon of perbenzylated monosaccharides with various anomerlc protecting groups, as well as natural disaccharldes and trisaccharides such as sucrose, raffinose, and melezltose In good yields (>80%).
