120694-96-4

Basic information

• Product Name: 6-(3-(2-hydroxymethylphenyl)-trans-prop-2-enyl)-5-hydroxy-2,3-dihydrobenzofuran
• Synonyms: 6-(3-(2-hydroxymethylphenyl)-trans-prop-2-enyl)-5-hydroxy-2,3-dihydrobenzofuran
• CAS NO: 120694-96-4
• Molecular Weight: 282.339
• Mol File: 120694-96-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 6-(3-(2-hydroxymethylphenyl)-trans-prop-2-enyl)-5-hydroxy-2,3-dihydrobenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(3-(2-hydroxymethylphenyl)-trans-prop-2-enyl)-5-hydroxy-2,3-dihydrobenzofuran(120694-96-4)
• EPA Substance Registry System: 6-(3-(2-hydroxymethylphenyl)-trans-prop-2-enyl)-5-hydroxy-2,3-dihydrobenzofuran(120694-96-4)

Safety Data

• Hazardous Substances Data: 120694-96-4(Hazardous Substances Data)

Upstream product

• 18454-54-1 2-Chlorocarbonyl-trans-cinnamoyl chloride 
• 135-19-3 β-naphthol 
• 55745-70-5 2,3-dihydro-benzofuran-5-carbaldehyde 
• 40492-52-2 2,3-dihydrobenzofuran-5-ol 
• 126080-73-7 (E)-3-(2-(hydroxymethyl)phenyl)prop-2-en-1-ol 
• 6630-33-7 ortho-bromobenzaldehyde 
• 124854-97-3 6-<3-(2-Cyanophenyl)-2-propenyl>-2,3-dihydro-5-hydroxybenzofuran 
• 124854-96-2 6-<3-(2-Bromophenyl)-2-propenyl>-2,3-dihydro-5-hydroxybenzofuran 
• 124854-94-0 (E)-3-(2-bromophenyl)-2-propen-1-ol 
• 124854-95-1 (E)-1-bromo-2-(3-bromoprop-1-en-1-yl)benzene 
• 91047-77-7 ethyl (2E)-3-(2-bromophenyl)prop-2-enoate 
• 18454-53-0 (E)-o-carboxycinnamic acid 
• 34288-40-9 2-(E)-[2-methoxycarbonylphenyl]acrylic acid methylester 
• 40492-53-3 2,3-dihydro-6-bromo-5-hydroxybenzofuran 

Downstream Products

• 120694-92-0 6-<3-<2-(hydroxymethyl)phenyl>propyl>-2,3-dihydro-5-benzofuranol 

Relevant articles and documents

PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS

The present application describes process for preparing an ortho-allylated hydroxy aryl compounds such as compounds of Formula (I) by reacting an allylic alcohol with a hydroxy aryl compound in the presence of aluminum compound selected from alumina and aluminum alkoxides and in a non-protic solvent wherein at least one carbon atom ortho to the hydroxy group in the hydroxy aryl compound is unsubstituted. The present application also includes compounds of Formula (I).

Synthesis of 6-(3-Aryl-2-propenyl)-2,3-dihydro-5-hydroxybenzofuran Derivatives by Cross Coupling Reactions

The synthesis of 6-(3-aryl-2-propenyl)-2,3-dihydro-5-hydroxybenzofuran derivatives by cross coupling between 6-bromo-2,3-dihydrobenzofurans and cinnamyl halides via organo-metallic compounds has been explored.Palladium catalysed reaction between benzofury

Substituted cinnamyl-2,3-dihydrobenzofuran and analogs useful as anti-inflammatory agents

Substituted cinnamyl-2,3-dihydrobenzofurans and analogs were prepared from the nucleophilic substitution of a cinnamylhalide with a 2,3-dihydrobenzofuran anion or an analog thereof. These compounds were found to be potent topical anti-inflammatory agents.