1207340-21-3Relevant articles and documents
Discovery and pharmacological profile of new 1H-indazole-3-carboxamide and 2H-pyrrolo[3,4-c]quinoline derivatives as selective serotonin 4 receptor ligands
Furlotti, Guido,Alisi, Maria Alessandra,Apicella, Claudia,Capezzone De Joannon, Alessandra,Cazzolla, Nicola,Costi, Roberta,Cuzzucoli Crucitti, Giuliana,Garrone, Beatrice,Iacovo, Alberto,Magarò, Gabriele,Mangano, Giorgina,Miele, Gaetano,Ombrato, Rosella,Pescatori, Luca,Polenzani, Lorenzo,Rosi, Federica,Vitiello, Marco,Di Santo, Roberto
, p. 9446 - 9466 (2013/01/16)
Since the discovery of the serotonin 4 receptor (5-HT4R), a large number of receptor ligands have been studied. The safety concerns and the lack of market success of these ligands have mainly been attributed to their lack of selectivity. In thi
COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT
-
Page/Page column 47-48, (2010/04/03)
Compound of formula (I) in which R1, R2 and R3 are defined in the following description, and the pharmaceutically acceptable acid-addition or base-addition salts thereof. The invention also relates to a process and an intermediate for preparing it, and to a pharmaceutical composition comprising it. The invention also relates to the use of a novel 2H-pyrrolo[3,4-c]quinoline compound for preparing a pharmaceutical composition that is active in the treatment of disturbances of the serotoninergic system.