1207362-36-4

Basic information

• Product Name: (S)-4-benzyl-3-hexanoyl-5,5-dimethyloxazolidin-2-one
• Synonyms: (S)-4-benzyl-3-hexanoyl-5,5-dimethyloxazolidin-2-one
• CAS NO: 1207362-36-4
• Molecular Weight: 303.401
• Mol File: 1207362-36-4.mol

Chemical Properties

• CAS DataBase Reference: (S)-4-benzyl-3-hexanoyl-5,5-dimethyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-benzyl-3-hexanoyl-5,5-dimethyloxazolidin-2-one(1207362-36-4)
• EPA Substance Registry System: (S)-4-benzyl-3-hexanoyl-5,5-dimethyloxazolidin-2-one(1207362-36-4)

Safety Data

• Hazardous Substances Data: 1207362-36-4(Hazardous Substances Data)

Upstream product

• 142-61-0 Hexanoyl chloride 
• 168297-85-6 (S)-4-benzyl-5,5-dimethyloxazolidin-2-one 
• 1373037-72-9 (S)-4-benzyl-3-(2-cyclohexylacetyl)-5,5-dimethyloxazolidin-2-one 
• 1373037-98-9 C₂₁H₂₆F₃NO₃ 
• 63-91-2 L-phenylalanine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 142-62-1 hexanoic acid 
• 1527484-89-4 C₂₂H₂₅NO₅ 
• 1527484-91-8 C₁₈H₂₅NO₄ 

Downstream Products

• 1207362-61-5 C₁₉H₂₄Cl₃NO₃ 
• 1207362-44-4 (S)-4-benzyl-3-(3,3-dimethylbutanoyl)-5,5-dimethyloxazolidin-2-one 
• 1312341-52-8 (S)-4-benzyl-5,5-dimethyl-N-(3-methylbutanoyl)-1,3-oxazolidin-2-one 
• 1373037-82-1 C₁₆H₁₈F₃NO₃ 
• 1373037-88-7 C₁₆H₁₈F₃NO₃ 
• 1373037-93-4 C₁₈H₁₇F₆NO₃ 
• 1373037-83-2 C₁₈H₁₈F₇NO₃ 
• 1373037-91-2 C₁₉H₁₇F₈NO₃ 
• 1373037-84-3 C₁₉H₁₈F₉NO₃ 
• 1373037-94-5 C₂₁H₁₇F₁₂NO₃ 
• 1373037-86-5 C₂₁H₁₈F₁₃NO₃ 
• 1373037-95-6 C₂₂H₁₇F₆NO₃ 
• 1373037-87-6 C₂₂H₁₈F₇NO₃ 
• 1373038-00-6 C₂₃H₂₄F₃NO₄ 

Relevant articles and documents

Asymmetric radical addition of TEMPO to titanium enolates

A mild method for a-hydroxylation of N-acyl oxazolidinones by asymmetric radical addition of the 2,2,6,6-tetramethylpiperidine N-oxy (TEMPO) radical to titanium enolates was developed. The high diastereoselectivity and broad scope of the reaction show synthetic utility for the a-hydroxylation of substrates that are not tolerant to strongly basic conditions.

A simple method for asymmetric trifluoromethylation of N-acyl oxazolidinones via Ru-catalyzed radical addition to zirconium enolates

A Ru-catalyzed direct thermal trifluoromethylation and perfluoroalkylation of N-acyloxazolidinones has been developed. The reaction is experimentally simple and requires inexpensive reagents while providing good yields of products with good levels of stereocontrol. Preliminary studies have shown notable compatibility with functional groups, aromatics, and certain heteroaromatic substituents. The described method provides a useful alternative for the synthesis of fluorinated materials in an experimentally convenient manner.

Valence tautomerism in titanium enolates: Catalytic radical haloalkylation and application in the total synthesis of neodysidenin

(Chemical Equation Presented) A direct ruthenium-catalyzed radical chloroalkylation of N-acyl oxazolidinones capitalizing on valence tautomerism of titanium enolates has been developed. The chloroalkylation method served as the centerpiece in the enantioselective total synthesis of trichloroleucine-derived marine natural product neodysidenin.