120757-13-3

Basic information

• Product Name: 4-(4-aMinophenyl)-3-Methyl-4-oxobutanoic acid hydrochloride
• Synonyms: 4-(4-aMinophenyl)-3-Methyl-4-oxobutanoic acid hydrochloride
• CAS NO: 120757-13-3
• Molecular Formula: C₁₁H₁₃NO₃*ClH
• Molecular Weight: 243.68676
• Mol File: 120757-13-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 187-188 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(4-aMinophenyl)-3-Methyl-4-oxobutanoic acid hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-aMinophenyl)-3-Methyl-4-oxobutanoic acid hydrochloride(120757-13-3)
• EPA Substance Registry System: 4-(4-aMinophenyl)-3-Methyl-4-oxobutanoic acid hydrochloride(120757-13-3)

Safety Data

• Hazardous Substances Data: 120757-13-3(Hazardous Substances Data)

Usage

General Description

4-(4-aminophenyl)-3-methyl-4-oxobutanoic acid hydrochloride is a chemical compound with the molecular formula C11H13NO3·HCl. It is an important intermediate in the production of pharmaceuticals and is commonly used in the synthesis of various drugs and active pharmaceutical ingredients. 4-(4-aMinophenyl)-3-Methyl-4-oxobutanoic acid hydrochloride has a wide range of applications in the pharmaceutical industry, as it can be used in the synthesis of analgesics, anti-inflammatory drugs, and other therapeutic agents. It is also used as a reagent in organic synthesis and drug discovery research. Additionally, it is a potent inhibitor of serine proteases, making it a valuable tool in biochemical and pharmacological research.

Upstream product

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Downstream Products

• 36725-28-7 6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone 
• 43191-77-1 6-(4-aminophenyl)-2,5-dimethyl-4,5-dihydropyridazine-3(2H)-one 
• 115344-47-3 2 cyano 1 methyl 3 [4 (4 methyl 6 oxo 1,4,5,6 tetrahydro 3 pyridazinyl)phenyl]guanidine 
• 99591-85-2 6-<4-(N'-cyano-S-methylisothioureido)phenyl>-5-methyl-4,5-dihydropyridazin-3(2H)-one 
• 112127-66-9 5-methyl-6-[4-(4-oxo-1,4-dihydropyridin-1-yl)phenyl]-4,5-dihydro-3(2H)-pyridazinone 

Relevant articles and documents

DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS

Compounds of formula (I) which are nicotinamide phosphoribosyltransferase (NAMPT) inhibitors and their use for the treatment of hyperproloferative diseases and/or disorders responsive to induction of cell death.

Studies on agents with vasodilator and β-blocking activities. IV

A series of novel pyridazinone derivatives (II) having a phenoxypropanolamine moiety was synthesized. Their hypotensive and β- blocking activities were evaluated after intravenous administration of the compounds to anesthetized rats. Among them, the 5-chloro-2-cyanophenoxy derivative (29) showed the promising dual activities and was selected for further studies.