1207981-11-0

Basic information

• Product Name: 2-((4-fluorophenyl)amino)-N-(4-hydroxyphenyl)benzamide
• Synonyms: 2-((4-fluorophenyl)amino)-N-(4-hydroxyphenyl)benzamide
• CAS NO: 1207981-11-0
• Molecular Weight: 322.339
• Mol File: 1207981-11-0.mol

Chemical Properties

• CAS DataBase Reference: 2-((4-fluorophenyl)amino)-N-(4-hydroxyphenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((4-fluorophenyl)amino)-N-(4-hydroxyphenyl)benzamide(1207981-11-0)
• EPA Substance Registry System: 2-((4-fluorophenyl)amino)-N-(4-hydroxyphenyl)benzamide(1207981-11-0)

Safety Data

• Hazardous Substances Data: 1207981-11-0(Hazardous Substances Data)

Upstream product

• 371-40-4 4-fluoroaniline 
• 88-65-3 2-bromobenzoic-acid 
• 54-60-4 4'-fluorodiphenylamine-2-carboxylic acid 
• 123-30-8 4-amino-phenol 

Downstream Products

• 1207981-01-8 N-(4-(2-aminopyrimidin-4-yloxy)phenyl)-2-(4-fluorophenylamino)benzamide 

Relevant articles and documents

Structure-guided design and development of novel N-phenylpyrimidin-2-amine derivatives as potential c-Met inhibitors

The HGF/Met signaling pathway is over-expressed in many types of cancers and closely related to oncogenesis and metastasis. Thus, we developed novel N-phenylpyrimidin-2-amine derivatives to test their inhibitory activities towards c-Met kinase, and most o

AURORA KINASE MODULATORS AND METHODS OF USE

The present invention relates to chemical compounds having a general formula I wherein A1-6, L1, L2, R1, R4-6 and n are defined herein, and synthetic intermediates, which are capable of modulating various protein kinase receptor enzymes and, thereby, influencing various disease states and conditions related to the activities of such kinases. For example, the compounds are capable of modulating Aurora kinase thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds and methods of treating disease states related to the activity of Aurora kinase.