1209455-90-2Relevant academic research and scientific papers
Dichotomous control of E/Z-geometry in intramolecular cyclization of o-alkynylbenzamide derivatives catalyzed by organic superbase P4-tBu in the presence/absence of water
Kanazawa, Chikashi,Terada, Masahiro
supporting information; experimental part, p. 1668-1672+1637 (2010/07/03)
E/Z does it! An intramolecular cycli-zation reaction of o-alkynylbenzamides that allows dichotomous control of E/Z-geometry has been developed using an organic superbase, P4-tBu, as a catalyst. The presence/absence of water along with the use of an organi
Silver-catalyzed intramolecular cyclization of o-(1-Alkynyl)benzamides: Efficient synthesis of (1H)-isochromen-1-imines
Liu, Guannan,Zhou, Yu,Ye, Deju,Zhang, Dengyou,Ding, Xiao,Jiang, Hualiang,Liu, Hong
supporting information; experimental part, p. 2605 - 2610 (2009/12/29)
An efficient avenue for the facile and atom-economic synthesis of (1H)-isochromen-1imines has been developed, and a broad spectrum of substrates can participate in the process effectively to produce the desired products in good yields. Significantly, this is the first report of the synthesis of (1H)-isochromen-l-imines that involves a silver(I)-catalyzed, regiocontrolled intramolecular addition of the carbonyl group of the amide moiety towards an alkyne.
