1084-95-3

Basic information

• Product Name: Benzoic acid, 2-(phenylethynyl)-
• CAS NO: 1084-95-3
• Molecular Formula: C15H10O2
• Molecular Weight: 222.243
• Mol File: 1084-95-3.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(phenylethynyl)-(1084-95-3)
• EPA Substance Registry System: Benzoic acid, 2-(phenylethynyl)-(1084-95-3)

Safety Data

• Hazardous Substances Data: 1084-95-3(Hazardous Substances Data)

Upstream product

• 1082852-47-8 2-(2-phenylethynyl)benzoic acid benzhydryl ester 
• 88-67-5 2-Iodobenzoic acid 
• 21890-32-4 tetrakis(phenylethynyl)tin 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 591-50-4 iodobenzene 
• 33577-99-0 2-ethynyl-benzoic acid methyl ester 
• 536-74-3 phenylacetylene 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 59046-72-9 o-(phenylethynyl)benzaldehyde 
• 124-38-9 carbon dioxide 
• 501-65-5 diphenyl acetylene 
• 21375-88-2 1-bromo-2-(phenylethenyl)benzene 
• 110166-71-7 ethyl 2-(phenylethynyl)benzoate 
• 33578-05-1 methyl 2-(phenylethynyl)benzoate 

Downstream Products

• 4809-08-9 3-phenyl-isocoumarin 
• 118520-78-8 4-iodo-3-phenyl-1H-isochromen-1-one 
• 208175-60-4 (S)-2-Phenylethynyl-N-(3-phenylpropan-1-ol-2-yl)benzamide 
• 1246168-32-0 3-benzyl-3-hydroxy-2-(pyridin-2-ylmethyl)isoindolin-1-one 
• 1246168-25-1 3-benzyl-3-hydroxy-2-(2-methoxybenzyl)isoindolin-1-one 
• 1246168-26-2 3-benzyl-3-hydroxy-2-(3,4,5-trimethoxybenzyl)isoindolin-1-one 
• 1246168-36-4 2-(2-(1H-indol-3-yl)ethyl)-3-benzyl-3-hydroxyisoindolin-1-one 
• 1246168-24-0 3-benzyl-3-hydroxy-2-(3-methoxybenzyl)isoindolin-1-one 
• 1246168-38-6 3-benzyl-3-hydroxy-2-(2-(5-methoxy-1H-indol-3-yl)ethyl)isoindolin-1-one 
• 1246168-30-8 3-benzyl-3-hydroxy-2-(naphthalen-1-ylmethyl)isoindolin-1-one 
• 1246168-34-2 3-benzyl-3-hydroxy-2-(4-methylphenethyl)isoindolin-1-one 
• 575-61-1 Isoaurone 
• 1246168-27-3 3-benzyl-3-hydroxy-2-(4-(trifluoromethyl)benzyl)isoindolin-1-one 
• 1246168-35-3 3-benzyl-2-(4-fluorophenethyl)-3-hydroxyisoindolin-1-one 

Relevant articles and documents

Cobalt(II)-Catalyzed Csp2-H Alkynylation/Annulation with Terminal Alkynes: Selective Access to 3-Methyleneisoindolin-1-one

A highly efficient cobalt(II)-catalyzed alkynylation/annulation of terminal alkynes assisted by an N,O-bidentate directing group is described. This protocol is characterized by wide substrate scope utilizing cheap cobalt catalysts, and offers a new approa

Use of Imidazo[1,5-a]pyridin-3-ylidene as a Platform for Metal-Imidazole Cooperative Catalysis: Silver-Catalyzed Cyclization of Alkyne-Tethered Carboxylic Acids

Silver complexes with 5-(4-(tert-butyl)-1H-imidazol-1-yl)-imidazo[1,5-a]pyridin-3-ylidene ligands were synthesized as metal-imidazole acid-base cooperative catalysts. Single crystal XRD analysis revealed that the silver atom was located in the vicinity of

Fe(III)-Catalyzed, Cyclizative Coupling between 2-Alkynylbenzoates and Carbinols: Rapid Generation of Polycyclic Isocoumarins and Phthalides and Mechanistic Study

FeCl3 catalyzed, highly regioselective cyclizative coupling of internal alkynes with alcohols has been reported for the rapid synthesis of structurally divergent, complex isocoumarins and phthalides respectively in intermolecular and intramolecular fashion. This strategy exhibited very high substrate scope and efficiency and proceeds through the simultaneous formation of C?O and C?C bonds. Observations from a series of control experiments supported a) the mechanism as Lewis acid catalyzed dual activation of ester and alcohol, b) the role of carbocation for the enhanced rates of cyclization, i. e., activation of alkyne by carbocation, and c) no role of HCl in the reported cascade process. (Figure presented.).

Green preparation method of 3-hydroxy isoindole-1-one compounds

The invention discloses a green preparation method of 3-hydroxy isoindole-1-one compounds, and belongs to the technical field of organic synthesis. The method comprises the following steps: adopting 2-alkynyl benzamide as a reaction substrate, adding a br