1209458-84-3Relevant academic research and scientific papers
HETEROCYCLIC COMPOUNDS AND METHODS OF USE
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Paragraph 000317, (2020/02/06)
The present invention discloses compounds useful in treatment of conditions associated with excessive activity of transforming growth factor beta (TGF-β), particularly type 1 or activin-like kinase 5 (ALK 5). Specifically the present invention discloses compound of formula (I) which exhibit inhibitory activity against ALK 5. Method of treating conditions associated with excessive activity (ALK 5) with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.
QUINOLINE-BASED KINASE INHIBITORS
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Page/Page column 90, (2015/11/02)
The present disclosure is generally directed to compounds of formula (I) which can inhibit AAKI (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAKI.
