120963-44-2Relevant academic research and scientific papers
Synthesis of the Carbocyclic Analogue of the Antiviral Nucleoside (E)-5-(2-Bromovinyl)-2'-deoxyuridine
Cookson, Richard C.,Dudfield, Philip J.,Scopes, David I.C.
, p. 399 - 404 (2007/10/02)
The cyclopentanecarboxylic acid (1) was converted via the isocyanate (2) and the urea (5) into carbocyclic uridine (12).Similarly, the α- and β-epimers of carbocyclic 2'-deoxyuridine, (19a) and (19b), were synthesized from the acids (13).Compounds (19a) and (19b) were furhter modified to afford carbocyclic (E)-5-(2-bromovinyl)-2'-deoxyuridine (25b) and its α-epimer (25a), respectively.
