120963-45-3 Usage
Chemical class
Pyrimidine derivatives
This compound belongs to a class of organic compounds that have a pyrimidine ring structure.
Cyclopentyl group
(1S,3R,4S)-3-hydroxy-4-(hydroxymethyl)cyclopentyl
The compound has a cyclopentyl group with three stereocenters (1S, 3R, and 4S), a hydroxyl functional group, and a hydroxymethyl functional group attached to it.
Iodine atom
5-iodo
An iodine atom is present at the 5th position of the pyrimidine ring, which may contribute to the compound's biological activities.
Functional groups
Hydroxyl and hydroxymethyl
The compound contains hydroxyl and hydroxymethyl functional groups, which can participate in various chemical reactions and interactions.
Potential drug candidate
Various biological activities
This compound has the potential to be a drug candidate due to its diverse biological activities, making it a promising molecule for further research.
Applications
Medicinal chemistry
Chemical structure
Promising for pharmaceutical research and development
The unique chemical structure of this compound makes it a valuable molecule for further research and development in the pharmaceutical industry.
Stereochemistry
Chiral centers
The compound has three chiral centers (1S, 3R, and 4S), which contribute to its stereochemistry and may affect its biological activity and interactions with other molecules.
Tautomerism
Possible existence of tautomeric forms
The compound may exist in different tautomeric forms, which could have different properties and biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 120963-45-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,9,6 and 3 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 120963-45:
(8*1)+(7*2)+(6*0)+(5*9)+(4*6)+(3*3)+(2*4)+(1*5)=113
113 % 10 = 3
So 120963-45-3 is a valid CAS Registry Number.
120963-45-3Relevant articles and documents
Cyclopentane-nucleobase coupling in the synthesis of carbocyclic L-nucleosides: Is a SN2-reaction an alternative to the mitsunobu-reaction?
Jessel,Hense,Meier
, p. 1181 - 1184 (2008/09/17)
Several carbocyclic L-nucleosides have been synthesized by coupling a cyclopentane-system with heterocycles according to a modified Mitsunobu-protocol. This reaction gave two regioisomers, the N1-alkylated product and an unwanted O2-product. A simple SN2-reaction has been investigated as an alternative for such couplings. Copyright Taylor & Francis Group, LLC.
Synthesis and Antiviral Activity of the Enantiomeric Forms of Carba-5-iodo-2'-deoxyuridine and Carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine
Balzarini, Jan,Baumgartner, Harald,Bodenteich, Michael,Clercq, Erik De,Griengl, Herfried
, p. 1861 - 1865 (2007/10/02)
Both enantiomers of the carbocyclic analogues of 5-iodo-2'-deoxyuridine (14 and ent-14) and of (E)-5-(2-bromovinyl)-2'-deoxyuridine (16 and ent-16) were synthesized by using (+)- or (-)-endo-norborn-5-en-2-yl acetate or butyrate, respectively, as starting
