121020-62-0

Basic information

• Product Name: (4-METHOXY-BENZYL)-PYRIDIN-2-YLMETHYL-AMINE
• Synonyms: (4-METHOXY-BENZYL)-PYRIDIN-2-YLMETHYL-AMINE;CHEMBRDG-BB 5561926;AKOS JY2016202;N-(4-METHOXYBENZYL)-N-(PYRIDIN-2-YLMETHYL)AMINE;UKRORGSYN-BB BBV-134533;(4-methoxybenzyl)(pyridin-2-ylmethyl)amine(SALTDATA: HBr);(4-Methoxyphenyl)-N-((pyridin-2-yl)Methyl)MethanaMine
• CAS NO: 121020-62-0
• Molecular Formula: C₁₄H₁₆N₂O
• Molecular Weight: 228.29
• Mol File: 121020-62-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 354°C at 760 mmHg
• Flash Point: 167.9°C
• Appearance: /
• Density: 1.092g/cm³
• Vapor Pressure: 3.44E-05mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: (4-METHOXY-BENZYL)-PYRIDIN-2-YLMETHYL-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-METHOXY-BENZYL)-PYRIDIN-2-YLMETHYL-AMINE(121020-62-0)
• EPA Substance Registry System: (4-METHOXY-BENZYL)-PYRIDIN-2-YLMETHYL-AMINE(121020-62-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 121020-62-0(Hazardous Substances Data)

Usage

General Description

(4-Methoxy-benzyl)-pyridin-2-ylmethyl-amine is a chemical compound with the molecular formula C14H16N2O. It is a derivative of benzylamine and pyridine, and is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. (4-METHOXY-BENZYL)-PYRIDIN-2-YLMETHYL-AMINE is commonly used in the production of antihistamines, as well as in the development of drugs for the treatment of various central nervous system disorders. Its unique structure and properties make it a valuable building block for the synthesis of diverse organic compounds, and it is frequently utilized in the pharmaceutical and chemical industries.

InChI:InChI=1/C14H16N2O/c1-17-14-7-5-12(6-8-14)10-15-11-13-4-2-3-9-16-13/h2-9,15H,10-11H2,1H3

Upstream product

• 3731-51-9 2-(Aminomethyl)pyridine 
• 123-11-5 4-methoxy-benzaldehyde 
• 2393-23-9 4-methoxy-benzylamine 
• 1204587-42-7 (p-MeO-C₆H₄)CH₂NCH-2-py 
• 1121-60-4 pyridine-2-carbaldehyde 
• 105-13-5 4-Methoxybenzyl alcohol 

Relevant articles and documents

Redox-Neutral Metal-Free Three-Component Carbonylative Dearomatization of Pyridine Derivatives with CO2

The TBD (1,3,5-triazabicyclodec-5-ene) assisted three-component carbonylation of pyridine-2-methanamines is documented by means of CO2 as a benign CO surrogate. The redox-neutral methodology enables the realization of densely functionalized imi

Preparation of the Ru3(CO)8-pyridine-alcohol cluster and its use for the selective catalytic transformation of primary to secondary amines

The synthesis of pyridine alcohol based ruthenium carbonyl clusters Ru3(hep)2(CO)8 (1), Ru3(hpp)2(CO)8 (2), and Ru3(bhmp-H)2(CO)8 (3) {hep-H = 2-(2-hydroxyethyl)pyridine, hpp-H = 2-(3-hydroxypropyl)pyridine and bhmp-H2 = 2,6-bis(hydroxymethyl)pyridine} has been carried out by the reaction of the corresponding pyridine-alcohol ligands with Ru3(CO)12. Clusters 1-3 have been characterized using elemental analysis, NMR, FT-IR, mass spectrometry and single-crystal X-ray structures. The clusters were explored for the selective catalytic transformation of primary amines into secondary amines using alcohols as the mono-alkylating agents via hydrogen transfer reactions. All three display efficient catalytic activity with 1 being the most effective.