1210866-46-8Relevant articles and documents
Nickel-catalysed para-CH activation of pyridine with switchable regioselective hydroheteroarylation of allylarenes
Lee, Wei-Chih,Chen, Chien-Hung,Liu, Cheng-Yuan,Yu, Ming-Shiuan,Lin, Yung-Huei,Ong, Tiow-Gan
, p. 17104 - 17107 (2015)
para-CH activation of pyridine with allylbenzene is described by Ni/Al cooperative catalysis in combination with a bulkier NHC ligand and a Lewis acid, leading to linear hydroheteroarylation products. Interestingly, the branch selectivity can be achieved by using the combination of a less sterically hindered amino-NHC ligand and AlMe3 through tandem reaction of facile alkene isomerization followed by a slow CH bond activation process.