121138-01-0

Basic information

• Product Name: 3-IODO-TETRAHYDRO-FURAN
• Synonyms: 3-IODO-TETRAHYDRO-FURAN;3-iodooxolane;Furan, tetrahydro-3-iodo-
• CAS NO: 121138-01-0
• Molecular Formula: C₄H₇IO
• Molecular Weight: 198
• Mol File: 121138-01-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 187.021 °C at 760 mmHg
• Flash Point: 66.908 °C
• Appearance: /
• Density: 1.931 g/cm³
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 3-IODO-TETRAHYDRO-FURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 3-IODO-TETRAHYDRO-FURAN(121138-01-0)
• EPA Substance Registry System: 3-IODO-TETRAHYDRO-FURAN(121138-01-0)

Safety Data

• Hazardous Substances Data: 121138-01-0(Hazardous Substances Data)

Usage

Description

3-IODO-TETRAHYDRO-FURAN is an organic compound that is characterized by the presence of a tetrahydrofuran ring with an iodine atom attached to the third carbon. It is a significant molecule in the field of organic chemistry and has potential applications in various industries due to its unique chemical properties.

Uses

Used in Chemical Synthesis:
3-IODO-TETRAHYDRO-FURAN is used as a synthetic intermediate for the development of various organic compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable building block in the synthesis of complex molecules.
Used in Pharmaceutical Industry:
3-IODO-TETRAHYDRO-FURAN is used as a key component in the development of new drugs. Its ability to undergo various chemical reactions enables the creation of novel pharmaceutical compounds with potential therapeutic applications.
Used in Research and Development:
3-IODO-TETRAHYDRO-FURAN is used as a research tool in the study of transition-metal-free Heck-type reactions between alkenes and alkyl iodides enabled by light in water. This application is crucial for advancing the understanding of these reactions and their potential applications in the synthesis of various organic compounds.

Physical Form

liquid

Upstream product

• 627-27-0 homoalylic alcohol 
• 13694-84-3 tetrahydro-3-furanyl tosylate 
• 453-20-3 3-Hydroxytetrahydrofuran 

Downstream Products

• 1442416-22-9 C₁₁H₁₃ClO₂ 
• 1616695-74-9 2-phenyl-3-(3-tetrahydrofuranyl)-2,1-borazaronaphthalene 

Relevant articles and documents

Photoinduced Palladium-Catalyzed Dicarbofunctionalization of Terminal Alkynes

Herein, a conceptually distinct approach was developed that allowed for the dicarbofunctionalization of alkynes at room temperature using simple, bench-stable alkyl iodides and a second molecule of alkyne as coupling partner. Specifically, the photochemical activation of palladium complexes enabled this strategic dicarbofunctionalization via addition of alkyl radicals from secondary and tertiary alkyl iodides and formation of an intermediate palladium vinyl complex that could undergo subsequent Sonogashira reaction with a second alkyne molecule. This alkylation–alkynylation sequence allowed the one-step synthesis of 1,3-enynes including heteroarenes and biologically active compounds with high efficiency without exogenous photosensitizers or oxidants and now opens up pathways towards cascade reactions via photochemical palladium catalysis.

Containing zinc binding moiety based EGFR tyrosine kinase inhibitors

Belonging to the technical field of medicine, the invention in particular relates to a zinc binding group-containing quinazolinyl EGFR (epidermal growth factor receptor) tyrosine kinase inhibitor shown as general formula (I), its deuterated compounds, pha

A transition-metal-free Heck-type reaction between alkenes and alkyl iodides enabled by light in water

A transition-metal-free coupling protocol between various alkenes and non-activated alkyl iodides has been developed by using photoenergy in water for the first time. Under UV irradiation and basic aqueous conditions, various alkenes efficiently couple with a wide range of non-activated alkyl iodides. A tentative mechanism, which involves an atom transfer radical addition process, for the coupling is proposed.