121155-45-1

Basic information

• Product Name: 3-Butenoic acid, 2-hydroxy-4-phenyl-, ethyl ester, (2S,3E)-
• CAS NO: 121155-45-1
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 121155-45-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3-Butenoic acid, 2-hydroxy-4-phenyl-, ethyl ester, (2S,3E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butenoic acid, 2-hydroxy-4-phenyl-, ethyl ester, (2S,3E)-(121155-45-1)
• EPA Substance Registry System: 3-Butenoic acid, 2-hydroxy-4-phenyl-, ethyl ester, (2S,3E)-(121155-45-1)

Safety Data

• Hazardous Substances Data: 121155-45-1(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 129029-61-4 2-hydroxy-4-phenylbut-3-enoic acid 
• 924-44-7 glyoxylic acid ethyl ester 
• 6783-05-7 trans-2-phenylvinylboronic acid 
• 1914-59-6 (E)-2-oxo-4-phenyl-3-butenoic acid 
• 17451-20-6 (E)-ethyl-2-oxo-4-phenylbut-3-enoate 
• 14371-10-9 (E)-3-phenylpropenal 
• 91129-16-7 rac-(E)-ethyl 2-hydroxy-4-phenylbut-3-enoate 
• 86659-03-2 ((E)-4,4-Diethoxy-buta-1,3-dienyl)-benzene 

Relevant articles and documents

Cobalt-Catalyzed Enantioselective Vinylation of Activated Ketones and Imines

We present here an unprecedented cobalt-catalyzed enantioselective vinylation of α-ketoesters, isatins, and imines to deliver a range of synthetically useful allylic alcohols and amines in high enantiopurity. This method employs commercially available and easy to handle catalysts and reagents and exhibits a high degree of practicality. The efficiency, selectivity, and operational simplicity of this catalytic system coupled with the substrate generality render this method a valuable tool in organic synthesis.

Stereochemical preference of Candida parapsilosis ATCC 7330 mediated deracemization: E- versus Z-aryl secondary alcohols

The stereochemical preference of the biocatalyst, Candida parapsilosis ATCC 7330, was investigated with respect to the E/Z configuration in the deracemization and the asymmetric reduction of aryl secondary alcohols and prochiral ketones, respectively. The

Highly enantioselective sequential hydrogenation of ethyl 2-Oxo-4-arylbut-3-enoate to ethyl 2-hydroxy-4-arylbutyrate

(Chemical Equation Presented) The hydrogenation of (E)-ethyl 2-oxo-4-arylbut-3-enoate with [NH2Me2]+[{RuCl [(S)-SunPhos]}2(μ-Cl3)] gave ethyl 2-hydroxy-4- arylbutyrate with 94-96% ee. Further investigation has proved that the hydrogenation proceeded via a sequential hydrogenation of C=O and C=C bonds, which is sensitive to the reaction temperature. Hydrolysis of ethyl 2-hydroxy-4-phenylbutyrate (ee 93%) provided the 2-hydroxy-4-phenylbutyric acid with 81% yield at 99% ee after a single recrystallization from 1, 2-dichloroethylene.