1211565-08-0 Usage
Uses
Used in Chemical Synthesis:
N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide is used as a catalyst for the asymmetric tandem aza-Michael addition-protonation reaction between 1-nitro cyclohexene and 4-methoxyaniline. This reaction forms the corresponding α-arylamino-β-nitro cyclohexane in a 35:65 trans/cis mixture, demonstrating the compound's potential as a catalyst in organic synthesis.
Used in Pharmaceutical Industry:
Due to its unique molecular structure and catalytic properties, N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide may have potential applications in the pharmaceutical industry. It could be used as a building block or intermediate in the synthesis of new drugs or drug candidates, particularly those targeting specific biological pathways or receptors.
Used in Material Science:
The unique structure and properties of N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide may also find applications in material science. It could be used as a component in the development of new materials with specific properties, such as improved stability, reactivity, or selectivity in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 1211565-08-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,1,5,6 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1211565-08:
(9*1)+(8*2)+(7*1)+(6*1)+(5*5)+(4*6)+(3*5)+(2*0)+(1*8)=110
110 % 10 = 0
So 1211565-08-0 is a valid CAS Registry Number.
1211565-08-0Relevant academic research and scientific papers
ONE-POT SYNTHESIS OF SQUARAMIDES
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Page/Page column 10; 12; 41, (2016/01/25)
The present invention refers to the first one-pot synthesis of squaramides. The one-pot synthesis of squaramides described herein is an easy and straightforward procedure to obtain squaramide derivatives which saves energy, avoids time consuming purificat
Squaramide-catalyzed enantioselective michael addition of diphenyl phosphite to nitroalkenes
Zhu, Ye,Malerich, Jeremiah P.,Rawal, Viresh H.
supporting information; experimental part, p. 153 - 156 (2010/03/30)
chemical equation presented Michael's a square: An easily prepared squaramide catalyst that promotes the highly enantioselective Michael addition reaction of diphenyl phosphite to a range of nitroalkenes is described. This method leads to chiral β-nitro phosphonates, which are precursors to biologically active β-amino phosphonic acids.
