1211587-40-4

Basic information

• Product Name: 3-Fluoro-4-methyl-2-pyridinecarboxylic acid
• Synonyms: 3-Fluoro-4-methyl-2-pyridinecarboxylic acid;3-Fluoro-4-methylpicolinic acid
• CAS NO: 1211587-40-4
• Molecular Formula: C7H6FNO2
• Molecular Weight: 155.1264432
• EINECS: -0
• Mol File: 1211587-40-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 282.7±35.0℃ (760 Torr)
• Flash Point: 124.7±25.9℃
• Appearance: /
• Density: 1.341±0.06 g/cm3 (20 ºC 760 Torr)
• CAS DataBase Reference: 3-Fluoro-4-methyl-2-pyridinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-4-methyl-2-pyridinecarboxylic acid(1211587-40-4)
• EPA Substance Registry System: 3-Fluoro-4-methyl-2-pyridinecarboxylic acid(1211587-40-4)

Safety Data

• Hazardous Substances Data: 1211587-40-4(Hazardous Substances Data)

Upstream product

• 881891-82-3 2-chloro-3-fluoro-4-methyl-pyridine 
• 884494-37-5 2-bromo-3-fluoro-4-methylpyridine 

Relevant articles and documents

Synthesis method of 3-fluoro-4-methylpyridine-2-carboxylic acid

The invention provides a synthesis method of 3-fluoro-4-methylpyridine-2-carboxylic acid, belonging to the field of chemical synthesis of medicines. According to the method, 2-halogenated-3-fluoro-4-methylpyridine is used as a raw material, and under the action of a catalyst and an alkali, carbonyl insertion coupling and a hydrolysis reaction are performed to obtain the target product 3-fluoro-4-methylpyridine-2-carboxylic acid. The method is short in reaction step and simple in synthesis operation, and the yield of the obtained product is relatively high.