1213236-30-6

Basic information

• Product Name: 3-methyl-1-(p-tolyl)-1H-indazole
• Synonyms: 3-methyl-1-(p-tolyl)-1H-indazole
• CAS NO: 1213236-30-6
• Molecular Weight: 222.29
• Mol File: 1213236-30-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-methyl-1-(p-tolyl)-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-1-(p-tolyl)-1H-indazole(1213236-30-6)
• EPA Substance Registry System: 3-methyl-1-(p-tolyl)-1H-indazole(1213236-30-6)

Safety Data

• Hazardous Substances Data: 1213236-30-6(Hazardous Substances Data)

Upstream product

• 551-93-9 2-aminoacetophenone 
• 23699-75-4 1-<2-<(4-Methylphenyl)amino>phenyl>ethanon 
• 2142-69-0 2-bromophenyl methyl ketone 
• 65763-66-8 1-Benzoyl-2-(4-methylphenyl)hydrazine 
• 1246849-40-0 (E)-1-(2-(p-tolylamino)phenyl)ethanone oxime 

Relevant articles and documents

DAST-promoted Beckmann rearrangement/intramolecular cyclization of acyclic ketoximes: Access to 2-oxazolines, benzimidazoles and benzoxazoles

The first example of DAST-promoted Beckmann rearrangement/intramolecular cyclization of acyclic ketoximes is described. This unique protocol represents a direct and effective pathway to 2-oxazolines, benzimidazoles and benzoxazoles in moderate to good yields.

Assembly of N, N -disubstituted hydrazines and 1-aryl-1 H-indazoles via copper-catalyzed coupling reactions

CuI-catalyzed coupling of N-acyl-N′-substituted hydrazines with aryl iodides takes place at 60-90 °C to afford N-acyl-N′,N′- disubstituted hydrazines regioselectively and thereby gives a facile method for assembling N,N-diaryl hydrazines. N-Acyl-N′-substituted hydrazines can also react with 2-bromoarylcarbonylic compounds at 60-125 °C under the catalysis of CuI/4-hydroxy-l-proline to provide 1-aryl-1H-indazoles.

METHOD OF SYNTHESIZING 1H-INDAZOLE COMPOUNDS

A method is provided for synthesizing 1H-indazole compounds in which aromatic carbonyl compounds are reacted with a nitrogen source to form oximes which are then converted to 1H-indazoles.